Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936619 | 0.79 | CES2 (0.35) | CES2 | |
| SCHEMBL26749077 | 0.79 | CES2 (0.48) | CES2 | |
| SCHEMBL12516790 | 0.77 | CES2 (0.38) | CES2 | |
| SCHEMBL11065093 | 0.77 | CES2 (0.61) | CES2 | |
| SCHEMBL10289059 | 0.76 | CES2 (0.40) | CES2 | |
| SCHEMBL26749027 | 0.76 | CES2 (0.45) | CES2 | |
| SCHEMBL26749062 | 0.76 | CES2 (0.45) | CES2 | |
| SCHEMBL27357474 | 0.75 | GAA (0.41) | CES2 | |
| SCHEMBL22198415 | 0.75 | CES2 (0.58) | CES2 | |
| SCHEMBL20932195 | 0.75 | CES2 (0.58) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014179144-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-8835427-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| US-8722678-B2 | Fungicidal oximes and hydrazones | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130030002-A1 | FUNGICIDAL OXIMES AND HYDRAZONES | E I DUPONT DE NEMOURS AND COMPANY (US) | 2013-01-31 | — | — | US | disclosed |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2012082580-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011146182-A1 | FUNGICIDAL OXIMES AND HYDRAZONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CYP51A1, Q6ZSR9, NOX1 | CES2 1179/4885ACACB 1210/4885 |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, NOX3, CYP1A1 | CES2 584/4885ACACB 3545/4885 |
| US-20130030002-A1 | FUNGICIDAL OXIMES AND HYDRAZONES | NOX1, QSOX1, XDH | CES2 599/4885ACACB 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.