Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932195 | 0.97 | CES2 (0.58) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL22198415 | 0.97 | CES2 (0.58) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL26279694 | 0.97 | CES2 (0.58) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL805276 | 0.89 | — | — | |
| SCHEMBL18768943 | 0.89 | CES2 (0.52) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL1618494 | 0.89 | CES2 (0.52) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL1417339 | 0.89 | ALDH1A1 (0.58) | CES2ALDH1A1TSHRTDP1THRB | |
| SCHEMBL19661922 | 0.88 | CES2 (0.77) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL20932198 | 0.88 | CES2 (0.70) | CES2ALDH1A1TSHRTDP1TRPA1 | |
| SCHEMBL18467759 | 0.87 | CES2 (0.50) | CES2ALDH1A1TSHRTDP1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59196319-A | — | — | None | — | — | JP | disclosed |
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-3922260-A2 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-12-14 | — | — | US | disclosed |
| WO-2017205191-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-9808011-B2 | Pentacyclic triterpene compounds and uses thereof | BIOVECTRA INC. (CA) | 2017-11-07 | — | — | US | disclosed |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20160165892-A1 | PENTACYCLIC TRITERPENE COMPOUNDS AND USES THEREOF | AGILENT TECHNOLOGIES, INC. | 2016-06-16 | — | — | US | disclosed |
| WO-2016081670-A2 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-05-26 | — | — | WO | disclosed |
| US-8765189-B2 | Organophosphorous and multivalent metal compound compositions and methods | Howmedica Osteonic Corp. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8658261-B2 | Composition, film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20120288446-A1 | ORGANOPHOSPHOROUS & MULTIVALENT METAL COMPOUND COMPOSITIONS & METHODS | HOWMEDICA OSTEONICS CORP. | 2012-11-15 | — | — | US | disclosed |
| US-20090109378-A1 | COMPOSITION, FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20070203165-A1 | COMPOUNDS AND METHODS FOR LOWERING THE ABUSE POTENTIAL AND EXTENDING THE DURATION OF ACTION OF A DRUG | CONTROLLED CHEMICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |
| JP-S59196319-A | PRODUCTION OF POLYAMIC ACID | HITACHI CHEM CO LTD | 1984-11-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | DOCK11, PAICS, RHOA | CES2 2441/4885ALDH1A1 1175/4885TSHR 3763/4885 |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CES2 2734/4885ALDH1A1 4716/4885TSHR 27/4885 |
| US-20160165892-A1 | PENTACYCLIC TRITERPENE COMPOUNDS AND USES THEREOF | GGPS1, LSS, ERG28 | CES2 1851/4885ALDH1A1 3126/4885TSHR 3279/4885 |
| US-20120288446-A1 | ORGANOPHOSPHOROUS & MULTIVALENT METAL COMPOUND COMPOSITIONS & METHODS | PHOSPHO1, PSPH, PTMS | CES2 3762/4885ALDH1A1 4733/4885TSHR 4060/4885 |
| US-20070203165-A1 | COMPOUNDS AND METHODS FOR LOWERING THE ABUSE POTENTIAL AND EXTENDING THE DURATION OF ACTION OF A DRUG | CRH, OPRK1, SI | CES2 14/4885ALDH1A1 544/4885TSHR 4533/4885 |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CES2 2734/4885ALDH1A1 4716/4885TSHR 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.