Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.58 |
| ▸ | HTR1A | P08908 | 6/20 | 0.50 |
| ▸ | DRD1 | P21728 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | DRD5 | P21918 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31223124 | 0.89 | DRD2 (0.73) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL256669 | 0.84 | DRD2 (0.58) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL256658 | 0.84 | DRD2 (0.82) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL256656 | 0.84 | DRD2 (0.78) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL15779804 | 0.83 | DRD2 (0.76) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL27571644 | 0.83 | DRD2 (0.76) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL19994717 | 0.83 | SIGMAR1 (0.49) | DRD2HTR1ADRD1DRD5DRD3 | |
| SCHEMBL9967721 | 0.82 | PRCP (0.48) | DRD2SIGMAR1KDM4ERECQLTDP1 | |
| SCHEMBL6249416 | 0.82 | DRD2 (0.53) | DRD2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL256671 | 0.81 | HRH3 (0.55) | DRD2HTR1ADRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | DHPS, FDPS, DPYD | DRD2 1749/4885HTR1A 3423/4885DRD1 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.