SCHEMBL9971083

SCHEMBL9971083

CCN1C(=O)C(F)(F)Oc2cc(F)c(N)cc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALPL P05186 1/20 0.33
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31
PARK7 Q99497 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704859 0.84 PGR (0.32)
SCHEMBL900663 0.84 PGR (0.32)
SCHEMBL25426279 0.81 POLB (0.46) KMT2A
SCHEMBL16275202 0.81 GABRG2 (0.34) BACE1
SCHEMBL26000623 0.80 MEN1 (0.35) MEN1KMT2AALPLPARK7
SCHEMBL9971075 0.79 MAPT (0.37) MEN1KMT2A
SCHEMBL28495237 0.79 CMA1 (0.43) MEN1KMT2A
SCHEMBL15056235 0.78
SCHEMBL9971037 0.78 ALPL (0.33) MEN1KMT2AALPL
SCHEMBL8600207 0.76 RORC (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012080239-A1 HERBICIDAL COMPOSITIONS BASF SE (DE) 2012-06-21 WO disclosed
WO-2011057935-A1 3-(3,4-DIHYDRO-2H-BENZO [1,4]OXAZIN-6-YL)-1H-PYRIMIDIN-2,4-DIONE COMPOUNDS AS HERBICIDES BASF SE (DE) 2011-05-19 WO disclosed
WO-2010145992-A1 HERBICIDAL BENZOXAZINONES BASF SE (DE) 2010-12-23 WO disclosed