Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of 2-Methoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methoxyethanol SCHEMBL28307253 | 0.96 | — | — | |
| 2-Methoxyethanol SCHEMBL27725382 | 0.96 | — | — | |
| 2-Methoxyethanol SCHEMBL310 | 0.96 | — | — | |
| 2-Methoxyethanol SCHEMBL1317307 | 0.96 | TSHR (0.47) | — | |
| 2-Methoxyethanol SCHEMBL28109691 | 0.93 | — | — | |
| 2-Methoxyethanol SCHEMBL5050349 | 0.92 | — | — | |
| 2-Methoxyethanol SCHEMBL3886889 | 0.92 | — | — | |
| 2-Methoxyethanol SCHEMBL7703885 | 0.92 | TSHR (0.44) | — | |
| 2-Methoxyethanol SCHEMBL6014126 | 0.92 | — | — | |
| 2-Methoxyethanol SCHEMBL21403186 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407355-B2 | Lignin processing | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2019-09-10 | — | — | US | claimed |
| US-5151160-A | Distillation of a mixture and extraction with a solvent | Berg, Lloyd (US) | 1992-09-29 | — | — | US | claimed |
| US-4100273-A | Antibiotic substance from Actinoplanes sarveparensis CBS 305.76 (antibiotic L 13365) | THE DOW CHEMICAL COMPANY (IT) | 1978-07-11 | — | — | US | claimed |
| US-11976163-B2 | Carbonate-linked surface modifying macromolecules | Evonik Canada Inc. (CA) | 2024-05-07 | — | — | US | disclosed |
| US-20240132498-A1 | CRYSTALLINE FORMS OF 5-(3,4-DIFLUOROBENZYL)-8-((1R,4R)-4-METHYLCYCLOHEXYL)-6,9-DIOXO-2,5,8-TRIAZASPIRO[3.5]NONANE-2-CARBALDEHYDE | CYTOKINETICS, INCORPORATED | 2024-04-25 | — | — | US | disclosed |
| CN-117756614-A | Method for refining polymethoxy dialkyl ether by dealdehyding | 青岛迈特达新材料有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-11578073-B2 | Xanthine analogs as potent anti-West Nile viral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2023-02-14 | — | — | US | disclosed |
| US-11495755-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210009502-A1 | CARBONATE-LINKED SURFACE MODIFYING MACROMOLECULES | Evonik Canada Inc. (CA) | 2021-01-14 | — | — | US | disclosed |
| EP-3762445-A1 | CARBONATE-LINKED SURFACE MODIFYING MACROMOLECULES | Evonik Canada Inc. (CA) | 2021-01-13 | — | — | EP | disclosed |
| US-20200399271-A1 | XANTHINE ANALOGS AS POTENT ANTI-WEST NILE VIRAL AGENTS | OREGON HEALTH AND SCIENCE UNIVERSITY | 2020-12-24 | — | — | US | disclosed |
| US-4880820-A | VIRICIDES, HERPES VIRUS | MERCK & CO., INC. (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0291244-A1 | Cyclic carbamate derivatives | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4775395-A | Integrated process for the treatment of a methane-containing wet gas in order to remove water therefrom | INSTITUT FRANCAIS DU PETROLE (FR) | 1988-10-04 | — | — | US | disclosed |
| US-4713383-A | ADENOSINE AND BENZODIAZEPINE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0130126-B1 | (S)-9-(2,3-DIHYDROXY-1-PROPOXYMETHYL) GUANINE AND ITS ACYL DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTIHERPETIC AGENTS | MERCK & CO. INC. (US) | 1987-08-26 | — | — | EP | disclosed |
| EP-0130126-A1 | (S)-9-(2,3-dihydroxy-1-propoxymethyl) guanine and its acyl derivatives, their preparation and their application as antiherpetic agents | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | disclosed |
| US-4393175-A | CROSSLINKING INHIBITION | DYNAPOL (US) | 1983-07-12 | — | — | US | disclosed |
| US-4163846-A | HERBICIDES | FISONS LIMITED (GB) | 1979-08-07 | — | — | US | disclosed |
| US-4100273-A | Antibiotic substance from Actinoplanes sarveparensis CBS 305.76 (antibiotic L 13365) | THE DOW CHEMICAL COMPANY (IT) | 1978-07-11 | — | — | US | disclosed |