Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442847 | 0.97 | MEN1 (0.41) | TOP2ATOP2BMEN1KMT2AKEAP1 | |
| SCHEMBL13304000 | 0.89 | EGFR (0.43) | KEAP1NFE2L2LTA4HGPR84KDM4E | |
| SCHEMBL13948907 | 0.88 | LTA4H (0.44) | TOP2ATOP2BMEN1KMT2AKEAP1 | |
| SCHEMBL9971766 | 0.87 | CYP1A2 (0.44) | KEAP1NFE2L2GPR84KDM4EALDH1A1 | |
| SCHEMBL18268266 | 0.82 | LTA4H (0.52) | MEN1KMT2ALTA4HCNR1CNR2 | |
| SCHEMBL6509895 | 0.82 | LTA4H (0.52) | MEN1KMT2ALTA4HCNR1CNR2 | |
| SCHEMBL19270226 | 0.82 | LTA4H (0.52) | MEN1KMT2ALTA4HCNR1CNR2 | |
| SCHEMBL28281806 | 0.82 | TUBB3 (0.48) | KEAP1NFE2L2GPR84KDM4EALDH1A1 | |
| SCHEMBL10065633 | 0.81 | LTA4H (0.47) | MEN1KMT2ALTA4HCNR1CNR2 | |
| SCHEMBL10053553 | 0.81 | TOP2A (0.38) | TOP2ATOP2BMEN1KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120153815-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153815-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20110175521-A1 | ORGANIC ELECTROLUMESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20110175521-A1 | ORGANIC ELECTROLUMESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20100160687-A1 | ORGANIC ELECTROLUMESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110175521-A1 | ORGANIC ELECTROLUMESCENCE DEVICE | SCO2, CHRM1, CHRM4 | TOP2A 3770/4885TOP2B 2167/4885MEN1 1808/4885 |
| US-20100160687-A1 | ORGANIC ELECTROLUMESCENCE DEVICE | SCO2, CHRM1, CHRM4 | TOP2A 3770/4885TOP2B 2167/4885MEN1 1808/4885 |
| US-20120153815-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | ARL1, RIF1, EML4 | TOP2A 4100/4885TOP2B 3435/4885MEN1 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.