SCHEMBL9972121

SCHEMBL9972121

CCc1cc(C=Cc2ccccc2)ccc1N(C=C(c1ccccc1)c1ccccc1)c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.40
RELA Q04206 1/20 0.39
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
TTR P02766 2/20 0.36
NPC1 O15118 3/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP3 P42574 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP1B1 Q16678 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9972117 0.83 TTR (0.43) CTDSP1RELAPTGS1PTGS2TTR
SCHEMBL9972132 0.81 TTR (0.43) CTDSP1RELAPTGS1PTGS2TTR
SCHEMBL9972128 0.79 RELA (0.50) CTDSP1RELATTRNPC1MAPT
SCHEMBL17486891 0.79 RELA (0.50) CTDSP1RELATTRNPC1MAPT
SCHEMBL13163966 0.78 RELA (0.48) CTDSP1RELATTRNPC1MAPT
SCHEMBL13909669 0.78 RELA (0.48) CTDSP1RELATTRNPC1MAPT
SCHEMBL13242000 0.77 ALDH1A1 (0.38) CTDSP1RELAPTGS1PTGS2TTR
SCHEMBL13986157 0.77 CTDSP1 (0.40) CTDSP1RELAMAPTL3MBTL1ALDH1A1
SCHEMBL13986161 0.76 NFE2L2 (0.45) CTDSP1RELAPTGS2TTRMAPT
SCHEMBL15076289 0.76 MEN1 (0.32) CTDSP1MAPTRAB9ASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed