Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972127 | 0.93 | TTR (0.33) | TTRPTGS1PTGS2ALOX5KDM4E | |
| SCHEMBL9972133 | 0.86 | TTR (0.35) | TTRPTGS1PTGS2ALOX5KDM4E | |
| SCHEMBL9972126 | 0.85 | PTGS2 (0.35) | PTGS2 | |
| SCHEMBL14081233 | 0.84 | APP (0.39) | KDM4EMAPTPOLBRAB9AL3MBTL1 | |
| SCHEMBL9972124 | 0.83 | TTR (0.35) | TTRPTGS1PTGS2ALOX5MAPT | |
| SCHEMBL9972132 | 0.83 | TTR (0.43) | TTRPTGS1PTGS2ALOX5MAPT | |
| SCHEMBL9972117 | 0.83 | TTR (0.43) | TTRPTGS1PTGS2ALOX5MAPT | |
| SCHEMBL13840791 | 0.82 | APP (0.36) | PTGS2KDM4EMAPTAPPCHAT | |
| SCHEMBL17735832 | 0.82 | APP (0.34) | PTGS1PTGS2KDM4EMAPTPOLB | |
| SCHEMBL14081210 | 0.81 | MAOB (0.39) | ALOX5KDM4EMAPTRAB9ACHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |