Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972125 | 0.85 | TTR (0.38) | PTGS2 | |
| SCHEMBL9972127 | 0.83 | TTR (0.33) | PTGS2 | |
| SCHEMBL9972130 | 0.83 | CYP19A1 (0.39) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL9972120 | 0.81 | PTGS2 (0.41) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL9972133 | 0.78 | TTR (0.35) | PTGS2 | |
| SCHEMBL11976760 | 0.77 | PTGS2 (0.40) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL11976765 | 0.75 | PTGS2 (0.44) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL11976761 | 0.75 | PTGS2 (0.44) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL11976770 | 0.74 | PTGS2 (0.34) | PTGS2CYP19A1CYP11B2ESR1CYP2D6 | |
| SCHEMBL12422879 | 0.74 | RELA (0.36) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |