Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972127 | 0.91 | TTR (0.33) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL9972125 | 0.86 | TTR (0.38) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL9972132 | 0.80 | TTR (0.43) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL9972117 | 0.80 | TTR (0.43) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL14081210 | 0.79 | MAOB (0.39) | ALOX5MAPTLMNAMAOBRAB9A | |
| SCHEMBL9972123 | 0.79 | ALDH1A1 (0.33) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL9972122 | 0.78 | SNCA (0.32) | TTRPTGS2ALOX5PTGS1MAPT | |
| SCHEMBL9972126 | 0.78 | PTGS2 (0.35) | PTGS2 | |
| SCHEMBL12422879 | 0.78 | RELA (0.36) | PTGS2ALOX5PTGS1MAPTLMNA | |
| SCHEMBL9972131 | 0.75 | MAOB (0.35) | LMNAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |