SCHEMBL9972673

SCHEMBL9972673

Cc1ccc(OC(=O)ONC(=O)OCc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 2/20 0.46
MAPT P10636 3/20 0.45
TP53 P04637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17473134 0.84 KMT2A (0.54) NPC1RAB9ALMNAMAPTL3MBTL1
SCHEMBL15317893 0.81 CA12 (0.55) CA12CA1CA2CA9NPC1
SCHEMBL6406957 0.81 CA12 (0.61) CA12CA1CA2CA9NPC1
SCHEMBL16558009 0.79 CA12 (0.47) CA12CA1CA2CA9NPC1
SCHEMBL9972687 0.78 RAB9A (0.51) CA12CA1CA2CA9NPC1
SCHEMBL19706606 0.78 MAPT (0.64) NPC1RAB9ALMNAMAPTL3MBTL1
SCHEMBL1947879 0.76 ALDH1A1 (0.65) CA12CA1CA2CA9NPC1
SCHEMBL11100708 0.76 CA12 (0.63) CA12CA1CA2CA9NPC1
SCHEMBL19709254 0.76 HTR2A (0.54) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4756378 0.75 CA12 (0.58) CA12CA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11813256-B2 High penetration prodrug compositions and pharmaceutical compositon thereof for treatment of pulmonary conditions PREMIER RESEARCH INTERNATIONAL, LLC 2023-11-14 US disclosed
US-11813256-B2 High penetration prodrug compositions and pharmaceutical compositon thereof for treatment of pulmonary conditions PREMIER RESEARCH INTERNATIONAL, LLC 2023-11-14 US disclosed
US-20230130980-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD. (CN) 2023-04-27 US disclosed
US-20230130980-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD. (CN) 2023-04-27 US disclosed
US-11485744-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds TECHFIELDS PHARMA CO., LTD. (CN) 2022-11-01 US disclosed
US-20210206782-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD. (CN) 2021-07-08 US disclosed
US-20190142818-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOISITON THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD 2019-05-16 US disclosed
US-10233197-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds TECHFIELDS PHARMA CO., LTD. (CN) 2019-03-19 US disclosed
US-20180222921-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS PREMIER RESEARCH INTERNATIONAL, LLC 2018-08-09 US disclosed
US-20180222921-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS PREMIER RESEARCH INTERNATIONAL, LLC 2018-08-09 US disclosed
US-9969751-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds TECHFIELDS PHARMA CO., LTD. (CN) 2018-05-15 US disclosed
US-9969751-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds TECHFIELDS PHARMA CO., LTD. (CN) 2018-05-15 US disclosed
US-20130018029-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD (CN) 2013-01-17 US disclosed
US-20120157371-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS PREMIER RESEARCH INTERNATIONAL, LLC 2012-06-21 US disclosed
US-20100040548-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD (CN) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11813256-B2 High penetration prodrug compositions and pharmaceutical compositon thereof for treatment of pulmonary conditions CPA3, PAH, HCAR2 CA12 622/4885CA1 914/4885CA2 658/4885
US-20180222921-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HPGDS CA12 4350/4885CA1 4406/4885CA2 3898/4885
US-20210206782-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HAMP CA12 4391/4885CA1 4418/4885CA2 4009/4885
US-11485744-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds SLC7A1, VIP, HPGDS CA12 4350/4885CA1 4406/4885CA2 3898/4885
US-20230130980-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HPGDS CA12 4350/4885CA1 4406/4885CA2 3898/4885
US-20130018029-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HAMP CA12 4391/4885CA1 4418/4885CA2 4009/4885
US-10233197-B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds SLC7A1, VIP, HAMP CA12 4391/4885CA1 4418/4885CA2 4009/4885
US-20100040548-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HAMP CA12 4391/4885CA1 4418/4885CA2 4009/4885
US-20120157371-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS SLC7A1, VIP, HPGDS CA12 4350/4885CA1 4406/4885CA2 3898/4885
US-20190142818-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOISITON THEREOF FOR TREATMENT OF PULMONARY CONDITIONS CPA3, HCAR2, HRH4 CA12 183/4885CA1 456/4885CA2 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.