SCHEMBL9974664

SCHEMBL9974664

CCc1ccc(OCCNC)cc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.62
HTR1D P28221 1/20 0.62
L3MBTL1 Q9Y468 3/20 0.54
KDM4E B2RXH2 1/20 0.53
MAPT P10636 2/20 0.51
LMNA P02545 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HTT P42858 1/20 0.49
CHRNB2 P17787 1/20 0.47
CHRNA4 P43681 1/20 0.47
ESR1 P03372 1/20 0.46
CYP19A1 P11511 1/20 0.46
HRH3 Q9Y5N1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13298494 0.94 HTR1B (0.63) HTR1BHTR1DL3MBTL1KDM4EMAPT
SCHEMBL24307302 0.87 HTR1D (0.49) HTR1BHTR1DHRH3
SCHEMBL23067890 0.86 DRD2 (0.60) L3MBTL1KDM4EMAPTLMNAALDH1A1
SCHEMBL10895841 0.85 ALDH1A1 (0.64) HTR1BHTR1DL3MBTL1LMNAALDH1A1
SCHEMBL5929490 0.83 MAPT (0.62) L3MBTL1KDM4EMAPTLMNAALDH1A1
SCHEMBL9124449 0.82 HTR1B (0.60) HTR1BHTR1DL3MBTL1KDM4ELMNA
SCHEMBL19632708 0.82 HTR1B (0.60) HTR1BHTR1DL3MBTL1KDM4ELMNA
SCHEMBL26126465 0.82 HTR1B (0.60) HTR1BHTR1DL3MBTL1KDM4ELMNA
SCHEMBL17308303 0.82 MAPT (0.54) L3MBTL1KDM4EMAPTLMNAALDH1A1
SCHEMBL20172578 0.82 HTR1B (0.55) HTR1BHTR1DL3MBTL1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US claimed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US claimed
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US disclosed
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2025-07-22 US disclosed
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2024-08-08 US disclosed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US disclosed
EP-3660004-B1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR ARVINAS OPERATIONS INC (US) 2023-02-22 EP disclosed
WO-2021046284-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. (US) 2021-03-11 WO disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-10807994-B2 Heterocyclic compounds and uses thereof NUVATION BIO INC. (US) 2020-10-20 US disclosed
WO-2018102067-A2 TAU-PROTEIN TARGETING PROTACS AND ASSOCIATED METHODS OF USE Arvinas, Inc. (US) 2018-06-07 WO disclosed
WO-2017197488-A1 LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME CYCLENIUM PHARMA INC. (CA) 2017-11-23 WO disclosed
WO-2017030814-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS Arvinas, Inc. (US) 2017-02-23 WO disclosed
US-20150361042-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2015-12-17 US disclosed
EP-2144881-B1 ISOQUINOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( COPD ) AND ASTHMA ASTRAZENECA AB (SE) 2012-06-20 EP disclosed
US-8012979-B2 Compounds and their uses 707 ASTRAZENECA AB (SE) 2011-09-06 US disclosed
WO-2011038261-A1 HETEROCYCLIC KINASE INHIBITORS SELEXAGEN THERAPEUTICS, INC. (US) 2011-03-31 WO disclosed
US-20090023746-A1 COMPOUNDS AND THEIR USES 707 ASTRAZENECA AB (SE) 2009-01-22 US disclosed
WO-2008122765-A1 NEW COMPOUNDS AND THEIR USES 707 ASTRAZENECA AB (SE) 2008-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 HTR1B 1932/4885HTR1D 2519/4885L3MBTL1 3154/4885
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 HTR1B 1932/4885HTR1D 2519/4885L3MBTL1 3154/4885
US-20090023746-A1 COMPOUNDS AND THEIR USES 707 CYP3A7, UGT1A7, UGT2B7 HTR1B 704/4885HTR1D 1614/4885L3MBTL1 4856/4885
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 HTR1B 1932/4885HTR1D 2519/4885L3MBTL1 3154/4885
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 HTR1B 1932/4885HTR1D 2519/4885L3MBTL1 3154/4885
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 HTR1B 1932/4885HTR1D 2519/4885L3MBTL1 3154/4885
US-20150361042-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT5, PRMT1, PRMT6 HTR1B 4464/4885HTR1D 4735/4885L3MBTL1 942/4885
US-10807994-B2 Heterocyclic compounds and uses thereof WEE1, WEE2, CCNE1 HTR1B 4011/4885HTR1D 3905/4885L3MBTL1 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.