Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.35 |
| ▸ | WNT3A | P56704 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998828 | 0.85 | AKT1 (0.34) | MTNR1AAKT1 | |
| SCHEMBL8481752 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL6583525 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL804188 | 0.74 | SLC9A1 (0.39) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL8374249 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL997623 | 0.69 | CTNNB1 (0.46) | CTNNB1WNT3AKDM4EAKT1MAPK1 | |
| SCHEMBL6582388 | 0.69 | MTNR1A (0.48) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL997528 | 0.68 | CTNNB1 (0.58) | CTNNB1WNT3AKDM4EAKT1MAPK1 | |
| SCHEMBL8291502 | 0.67 | MTNR1A (0.46) | MTNR1AMTNR1BCTNNB1WNT3AMAPK1 | |
| SCHEMBL6582231 | 0.67 | MTNR1A (0.43) | MTNR1AMTNR1BCTNNB1WNT3AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |