Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975647 | 0.89 | CHRNA7 (0.53) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL22857712 | 0.77 | CYP3A4 (0.50) | CHRNA7CYP3A4USP2ALDH1A1CYP2D6 | |
| SCHEMBL28697423 | 0.76 | USP2 (0.50) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL26407337 | 0.76 | CHRNA7 (0.55) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL23555238 | 0.75 | CHRNA7 (0.46) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL1107775 | 0.72 | USP2 (0.55) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL9975646 | 0.71 | LMNA (0.46) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| Ammonia Solution, Strong SCHEMBL28324490 | 0.71 | USP2 (0.53) | CHRNA7DRD2SIGMAR1CYP3A4USP2 | |
| SCHEMBL2946610 | 0.70 | USP2 (0.54) | CHRNA7USP2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22657654 | 0.69 | USP2 (0.52) | CHRNA7DRD2SIGMAR1CYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11832508-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2023-11-28 | — | — | US | disclosed |
| US-10403832-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2019-09-03 | — | — | US | disclosed |
| US-8945725-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2015-02-03 | — | — | US | disclosed |
| US-20120153816-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11832508-B2 | Organic electroluminescence device | LAGE3, L1CAM, LEF1 | CHRNA7 652/4885DRD2 2332/4885SIGMAR1 3503/4885 |
| US-20120153816-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, LAGE3, LEF1 | CHRNA7 870/4885DRD2 2594/4885SIGMAR1 3166/4885 |
| US-10403832-B2 | Organic electroluminescence device | LAGE3, L1CAM, LEF1 | CHRNA7 687/4885DRD2 2362/4885SIGMAR1 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.