Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitroethane SCHEMBL6381909 | 0.83 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL3331716 | 0.82 | GABRP (0.48) | LMNACPA1MEN1BLMHBB | |
| SCHEMBL28060367 | 0.80 | TSHR (0.37) | ALDH1A1CA1CPA1 | |
| SCHEMBL20261755 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CA1LMNASLC15A2MEN1 | |
| SCHEMBL4434496 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL17673923 | 0.77 | TSHR (0.46) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23829566 | 0.76 | — | — | |
| SCHEMBL21549962 | 0.76 | GABRR1 (0.32) | CPA1 | |
| SCHEMBL19283717 | 0.75 | MEN1 (0.34) | CA1LMNACPA1MEN1BLM | |
| SCHEMBL3239628 | 0.74 | LMNA (0.41) | ALDH1A1LMNAMEN1BLMHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941846-A | Preparation of nitrocarbonyl compounds | TEXACO INC. (US) | 1976-03-02 | — | — | US | claimed |
| US-9421513-B2 | Catalyst-coated support, method for the production thereof, a reactor equipped therewith, and use thereof | THYSSENKRUPP UHDE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-8729277-B2 | Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729277-B2 | Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729277-B2 | Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2014-05-20 | — | — | US | disclosed |
| US-8338325-B2 | Tethered catalyst processes in microchannel reactors and systems containing a tethered catalyst or tethered chiral auxiliary | VELOCYS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338325-B2 | Tethered catalyst processes in microchannel reactors and systems containing a tethered catalyst or tethered chiral auxiliary | VELOCYS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338325-B2 | Tethered catalyst processes in microchannel reactors and systems containing a tethered catalyst or tethered chiral auxiliary | VELOCYS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120198769-A1 | CATALYST-COATED SUPPORT, METHOD FOR THE PRODUCTION THEREOF, A REACTOR EQUIPPED THEREWITH, AND USE THEREOF | THYSSENKRUPP INDUSTRIAL SOLUTIONS AG (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120157692-A1 | Processes for the Synthesis of Gamma Nitrocarbonyl and Gamma Dicarbonyl Compounds and Their Pyrrole Derivatives | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-06-21 | — | — | US | disclosed |
| US-4066780-A | Pyranoindole derivatives as antiulcer agents | AYERST MCKENNA AND HARRISON LTD. (CA) | 1978-01-03 | — | — | US | disclosed |
| US-4066779-A | ANTIDEPRESSANT, ANTIULCER | AYERST, MCKENNA AND HARRISON LTD. (CA) | 1978-01-03 | — | — | US | disclosed |
| US-4056538-A | ANTIDEPRESSANTS, ANTIULCER AGENTS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1977-11-01 | — | — | US | disclosed |
| US-4056537-A | CYCLIZATION, ACID CATALYST | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-01 | — | — | US | disclosed |
| US-4041169-A | TREATING AND PREVENTING ULCERS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-08-09 | — | — | US | disclosed |
| US-4012511-A | ANTIULCER AGENTS | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-03-15 | — | — | US | disclosed |
| US-4003913-A | ANTIDEPRESSANTS, ANTIULCER AGENTS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-01-18 | — | — | US | disclosed |
| US-3995052-A | Indenopyran- and indenothiopyranalkylamines III in the treatment of depression | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-11-30 | — | — | US | disclosed |
| US-3962236-A | ANTIDEPRESSANTS, ANTI-ULCER | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-06-08 | — | — | US | disclosed |
| US-3941846-A | Preparation of nitrocarbonyl compounds | TEXACO INC. (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157692-A1 | Processes for the Synthesis of Gamma Nitrocarbonyl and Gamma Dicarbonyl Compounds and Their Pyrrole Derivatives | DHPS, DNPH1, DDT | ALDH1A1 2354/4885CA1 3082/4885LMNA 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.