Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15762727 | 0.90 | ALDH1A1 (0.48) | KDM4EKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL13380665 | 0.84 | KDM4E (0.48) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL24983721 | 0.82 | ALDH1A1 (0.62) | KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL4457286 | 0.82 | ALDH1A1 (0.48) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24967267 | 0.82 | ACACB (0.45) | KDM4EKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL29339569 | 0.82 | RXRA (0.46) | KDM4EKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL27814526 | 0.82 | KMT2A (0.48) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28589056 | 0.82 | KDM4E (0.47) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28589062 | 0.82 | KDM4E (0.47) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL23185452 | 0.81 | KMT2A (0.48) | KDM4EKMT2AMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739047-B2 | Alpha-truxillic acid derivatives and pharmaceutical compositions thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-29 | — | — | US | disclosed |
| US-8779191-B2 | Methods and compositions for preparing lisdexamfetamine and salts thereof | CAMBREX CHARLES CITY, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120190880-A1 | METHODS AND COMPOSITIONS FOR PREPARATION OF AMPHETAMINE CONJUGATES AND SALTS THEREOF | BLUE OWL CAPITAL CORPORATION, AS NEW AGENT | 2012-07-26 | — | — | US | disclosed |
| US-20120157706-A1 | Methods and Compositions for Preparing Lisdexamfetamine and Salts Thereof | AVISTA PHARMA SOLUTIONS, INC. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190880-A1 | METHODS AND COMPOSITIONS FOR PREPARATION OF AMPHETAMINE CONJUGATES AND SALTS THEREOF | PNMT, COMT, DDT | KDM4E 167/4885KMT2A 34/4885MAPT 350/4885 |
| US-20120157706-A1 | Methods and Compositions for Preparing Lisdexamfetamine and Salts Thereof | SLC6A3, COMT, LPXN | KDM4E 587/4885KMT2A 303/4885MAPT 60/4885 |
| US-11739047-B2 | Alpha-truxillic acid derivatives and pharmaceutical compositions thereof | FABP1, FABP2, FABP4 | KDM4E 4346/4885KMT2A 4609/4885MAPT 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.