Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719904 | 0.76 | MAPK1 (0.49) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL28975450 | 0.74 | MAPK1 (0.48) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL8900397 | 0.74 | ADRA1A (0.53) | KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL9589367 | 0.71 | ALDH1A1 (0.55) | KMT2AALDH1A1MEN1L3MBTL1LMNA | |
| SCHEMBL24983762 | 0.70 | L3MBTL1 (0.50) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL500044 | 0.70 | AKR1C3 (0.54) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL12499466 | 0.70 | AKR1C3 (0.54) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL7166547 | 0.70 | AKR1C3 (0.54) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL18287899 | 0.70 | MAPT (0.46) | KDM4EKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL7311711 | 0.70 | KMT2A (0.44) | MAPK1KDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160021-A2 | FULLERENE DERIVATIVES | KONARKA TECHNOLOGIES, INC. (US) | 2011-12-22 | — | — | WO | claimed |
| WO-2011160021-A2 | FULLERENE DERIVATIVES | KONARKA TECHNOLOGIES, INC. (US) | 2011-12-22 | — | — | WO | disclosed |