Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 3/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340259 | 0.89 | LMNA (0.49) | LMNAPOLBWDR5STING1CYP3A4 | |
| SCHEMBL1136137 | 0.88 | LMNA (0.54) | LMNAPOLBWDR5STING1CYP3A4 | |
| SCHEMBL1136025 | 0.85 | LMNA (0.51) | LMNAPOLBWDR5STING1CYP3A4 | |
| SCHEMBL1136177 | 0.84 | LMNA (0.64) | LMNAPOLBWDR5STING1CHRM3 | |
| SCHEMBL13491717 | 0.84 | LMNA (0.52) | LMNAPOLBWDR5CHRM3GAA | |
| SCHEMBL16618150 | 0.83 | LMNA (0.63) | LMNAPOLBWDR5CHRM3NTRK1 | |
| SCHEMBL1144935 | 0.82 | LMNA (0.53) | LMNAPOLBWDR5STING1CYP3A4 | |
| SCHEMBL3086673 | 0.82 | LMNA (0.46) | LMNAPOLBWDR5CYP3A4NR3C1 | |
| SCHEMBL303303 | 0.81 | LMNA (0.53) | LMNAPOLBWDR5STING1CHRM3 | |
| SCHEMBL29445400 | 0.81 | LMNA (0.48) | LMNAPOLBWDR5CYP3A4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |