SCHEMBL998025

SCHEMBL998025

O=S(=O)(O)c1c(F)c(F)c(O)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA13 Q8N1Q1 3/20 0.38
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
DAPK1 P53355 1/20 0.33
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4578502 0.97 CA1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL31388915 0.97 CA1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL23340283 0.92 CA1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL2875483 0.88 CA2 (0.48) CA1CA2MMP1MMP2MMP9
SCHEMBL352595 0.86 CA1 (0.44) CA1CA2MMP1MMP2MMP9
SCHEMBL36242 0.85 CA2 (0.52) CA1CA2MMP1MMP2MMP9
SCHEMBL21522547 0.82 CA2 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL3168827 0.82 CA2 (0.50) CA1CA2MMP1MMP2MMP9
Ammonia Solution, Strong SCHEMBL21384843 0.82 CA2 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL21522549 0.82 CA2 (0.50) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794583-A Bisbenzimidazole STING agonist immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-03-29 CN claimed
EP-3081564-B1 INDOLE DERIVATIVES AS LABELING DYE FOR BIOMOLECULE PIERCE BIOTECHNOLOGY INC (US) 2019-07-10 EP claimed
EP-2686680-B1 FLUORESCENT DYES, FLUORESCENT DYE KITS, AND METHODS OF PREPARING LABELED MOLECULES BIOTIUM INC (US) 2018-06-13 EP claimed
US-9814759-B2 Pharmaceutical composition comprising recombinant hemoglobin protein or subunit-based therapeutic agent for cancer targeting treatment CHEER GLOBAL LTD. (HK) 2017-11-14 US claimed
US-9732101-B2 Bioreversible boronates for delivery of molecules into cells WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-08-15 US claimed
EP-3001813-A1 PHARMACEUTICAL COMPOSITION COMPRISING MODIFIED HEMOGLOBIN- BASED THERAPEUTIC AGENT FOR CANCER TARGETING TREATMENT AND DIAGNOSTIC IMAGING Vision Global Holdings Ltd. (CN) 2016-04-06 EP claimed
US-20160024122-A1 BIOREVERSIBLE BORONATES FOR DELIVERY OF MOLECULES INTO CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-01-28 US claimed
US-20160000864-A1 PHARMACEUTICAL COMPOSITION COMPRISING RECOMBINANT HEMOGLOBIN PROTEIN OR SUBUNIT-BASED THERAPEUTIC AGENT FOR CANCER TARGETING TREATMENT CHEER GLOBAL LTD. (HK) 2016-01-07 US claimed
WO-2014186301-A1 PHARMACEUTICAL COMPOSITION COMPRISING MODIFIED HEMOGLOBIN- BASED THERAPEUTIC AGENT FOR CANCER TARGETING TREATMENT AND DIAGNOSTIC IMAGING VISION GLOBAL HOLDINGS LTD. (CN) 2014-11-20 WO claimed
US-20140335018-A1 PHARMACEUTICAL COMPOSITION COMPRISING MODIFIED HEMOGLOBIN-BASED THERAPEUTIC AGENT FOR CANCER TARGETING TREATMENT AND DIAGNOSTIC IMAGING VISION GLOBAL HOLDINGS LTD. (HK) 2014-11-13 US claimed
EP-1792949-A2 Hydrophilic marker on the basis of diastereomeric cyanines Dyomics GmbH (DE) 2007-06-06 EP claimed
US-20060239922-A1 WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS GE HEALTHCARE UK LIMITED (GB) 2006-10-26 US claimed
WO-2006111726-A1 WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS GE HEALTHCARE UK LIMITED (GB) 2006-10-26 WO claimed
US-20060057573-A1 Methods and reagents for detecting target binding by nucleic acid ligands SOMALOGIC, INC (US) 2006-03-16 US claimed
US-20050085622-A1 Method for modifying protein or peptide C-terminal SHIMADZU CORPORATION (JP) 2005-04-21 US claimed
EP-1481090-A1 METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS SomaLogic, Inc. (US) 2004-12-01 EP claimed
EP-1476753-A2 FUNCTIONALIZED COMPOSITIONS FOR IMPROVED IMMOBILIZATION Luminex Corporation (US) 2004-11-17 EP claimed
US-20040039201-A1 Functionalized compositions for improved immobilization LUMINEX CORPORATION 2004-02-26 US claimed
WO-2003084982-A2 FUNCTIONALIZED COMPOSITIONS FOR IMPROVED IMMOBILIZATION LUMINEX CORPORATION (US) 2003-10-16 WO claimed
WO-2003070984-A1 METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS SOMALOGIC, INC. (US) 2003-08-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060239922-A1 WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS TPD52L2, MRPL21, MRPL9 CA1 1035/4885CA2 1581/4885MMP1 2866/4885
US-20160024122-A1 BIOREVERSIBLE BORONATES FOR DELIVERY OF MOLECULES INTO CELLS BAG6, BCAP31, PHB1 CA1 2615/4885CA2 853/4885MMP1 3916/4885
US-20050085622-A1 Method for modifying protein or peptide C-terminal PTMS, DNPEP, PTMA CA1 960/4885CA2 3851/4885MMP1 2940/4885
US-20040039201-A1 Functionalized compositions for improved immobilization ILK, EPCAM, ICAM1 CA1 431/4885CA2 629/4885MMP1 3056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.