Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980383 | 0.91 | LMNA (0.41) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL9980382 | 0.85 | USP2 (0.36) | CA1CA2CA7CA13MAPK8 | |
| SCHEMBL9980404 | 0.79 | STK4 (0.39) | ADORA3ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL12067896 | 0.78 | TNNI3K (0.44) | — | |
| SCHEMBL9980411 | 0.76 | CYP1A2 (0.45) | CA1CA2CA7CA13MAPK8 | |
| SCHEMBL1805695 | 0.71 | MAPK1 (0.55) | LMNAMAPT | |
| SCHEMBL12067067 | 0.70 | TNNI3K (0.55) | — | |
| SCHEMBL9980375 | 0.68 | TNNI3K (0.40) | CA1CA2CA7CA13LMNA | |
| SCHEMBL19475696 | 0.66 | FYN (0.40) | ADORA2ACLK4MAPTHSP90AA1HSP90AB1 | |
| SCHEMBL2226058 | 0.65 | TNNI3K (0.49) | CDK1CCNB1LMNAMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |