Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980411 | 0.91 | CYP1A2 (0.45) | USP2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9980405 | 0.85 | CCNB2 (0.34) | CLK4LMNAMAPTCA1CA2 | |
| SCHEMBL12065551 | 0.78 | TNNI3K (0.44) | — | |
| SCHEMBL9980486 | 0.78 | FFAR2 (0.33) | USP2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9980383 | 0.76 | LMNA (0.41) | LMNAMAPK1MAPTCA1CA2 | |
| SCHEMBL1805695 | 0.71 | MAPK1 (0.55) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL12067895 | 0.70 | TNNI3K (0.55) | — | |
| SCHEMBL9980375 | 0.68 | TNNI3K (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2CA1 | |
| SCHEMBL9980448 | 0.65 | LRRK2 (0.42) | ALDH1A1LRRK2CA1CA2TTK | |
| SCHEMBL2226058 | 0.65 | TNNI3K (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |