Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739957 | 0.91 | CTSL (0.39) | OPRM1CNR2CNR1SMN1; SMN2 | |
| SCHEMBL812375 | 0.83 | CTSL (0.40) | OPRM1CNR2CNR1SMN1; SMN2 | |
| SCHEMBL12479482 | 0.82 | CNR1 (0.34) | FPR2SCN9ACNR2CNR1MAPT | |
| SCHEMBL12029926 | 0.81 | ANO1 (0.41) | HDAC1HDAC2ANO1 | |
| SCHEMBL2387897 | 0.80 | CNR1 (0.37) | CNR2CNR1HDAC1HDAC2MEN1 | |
| SCHEMBL27781318 | 0.80 | CNR2 (0.34) | CNR2CNR1MAPTHDAC4ALDH1A1 | |
| SCHEMBL12029984 | 0.80 | OPRM1 (0.38) | FPR2SCN9AOPRM1HDAC1HDAC2 | |
| SCHEMBL2375831 | 0.79 | FPR2 (0.36) | FPR2SCN9AOPRM1CNR2CNR1 | |
| SCHEMBL8862797 | 0.78 | POLB (0.40) | L3MBTL1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8862538 | 0.78 | POLB (0.40) | L3MBTL1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-9000189-B2 | Biphenyl-substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | disclosed |
| US-9000189-B2 | Biphenyl-substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20110306499-A1 | Biphenyl-Substituted Spirocyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110306499-A1 | Biphenyl-Substituted Spirocyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| WO-2008067911-A1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306499-A1 | Biphenyl-Substituted Spirocyclic Ketoenols | KCNE1, PDHX, PIKFYVE | FPR2 4771/4885SCN9A 2353/4885OPRM1 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.