Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739957 | 0.93 | CTSL (0.39) | CTSLCTSBCTSSCNR2CNR1 | |
| SCHEMBL7098853 | 0.87 | SMN1; SMN2 (0.37) | CTSLCTSBCTSSSMN1; SMN2OPRM1 | |
| SCHEMBL8862538 | 0.86 | POLB (0.40) | SMN1; SMN2 | |
| SCHEMBL8862966 | 0.86 | POLB (0.40) | SMN1; SMN2 | |
| SCHEMBL8862797 | 0.86 | POLB (0.40) | SMN1; SMN2 | |
| SCHEMBL8863072 | 0.85 | L3MBTL1 (0.41) | SMN1; SMN2OPRM1 | |
| SCHEMBL811961 | 0.83 | WNT3A (0.43) | CTSLCTSBCTSSCNR2CNR1 | |
| SCHEMBL9980974 | 0.83 | FPR2 (0.40) | CNR2CNR1SMN1; SMN2OPRM1 | |
| SCHEMBL1476383 | 0.82 | CTSB (0.39) | CTSLCTSBCTSSSMN1; SMN2OPRM1 | |
| SCHEMBL8862748 | 0.77 | L3MBTL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7105471-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER | 2006-06-08 | — | — | US | disclosed |
| US-20040167031-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2004-08-26 | — | — | US | disclosed |
| US-6716832-B2 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2002-12-12 | — | — | US | disclosed |
| US-6417370-B1 | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, KCNQ2 | CTSL 1180/4885CTSB 2679/4885CTSS 1339/4885 |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | CTSL 750/4885CTSB 2477/4885CTSS 1278/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | CTSL 750/4885CTSB 2477/4885CTSS 1278/4885 |
| US-20040167031-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | CTSL 1285/4885CTSB 2837/4885CTSS 1381/4885 |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | CTSL 1345/4885CTSB 2763/4885CTSS 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.