Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986849 | 0.85 | KDM4E (0.41) | ALDH1A1HSP90AA1CA1CA2KDM4E | |
| SCHEMBL9986769 | 0.83 | CA12 (0.42) | ALPLALPIALDH1A1CA1CA2 | |
| SCHEMBL9986035 | 0.82 | KDM4E (0.41) | ALPLALDH1A1HSP90AA1PARLKDM4E | |
| SCHEMBL9986257 | 0.75 | ALPL (0.49) | ALPLALPIMAOAALDH1A1HSP90AA1 | |
| SCHEMBL15790433 | 0.69 | CYP2C9 (0.53) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL15022229 | 0.69 | CA1 (0.47) | ALPLALPIMAOAALDH1A1HSP90AA1 | |
| SCHEMBL929164 | 0.68 | ALPL (0.53) | ALPLALPIMAOAALDH1A1HSP90AA1 | |
| SCHEMBL2234824 | 0.68 | HSP90AA1 (0.63) | ALPLALPIMAOAALDH1A1HSP90AA1 | |
| SCHEMBL1061125 | 0.68 | HSP90AA1 (0.63) | ALPLALPIMAOAALDH1A1HSP90AA1 | |
| SCHEMBL18263202 | 0.67 | CA2 (0.49) | ALPLALPIMAOAALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | PREP, ADAM10, DNPEP | ALPL 500/4885ALPI 769/4885MAOA 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.