SCHEMBL15022229

SCHEMBL15022229

O=[N+]([O-])c1ccc(S(=O)(=O)Oc2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 7/20 0.47
▸ CA2 P00918 7/20 0.47
▸ CA9 Q16790 6/20 0.47
▸ CA12 O43570 4/20 0.47
▸ CA14 Q9ULX7 4/20 0.47
▸ CA5A P35218 4/20 0.47
▸ CA3 P07451 3/20 0.47
▸ CA4 P22748 3/20 0.47
▸ CA6 P23280 3/20 0.47
▸ CA7 P43166 3/20 0.47
▸ CA13 Q8N1Q1 3/20 0.47
▸ CA5B Q9Y2D0 3/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ HSP90AA1 P07900 1/20 0.47
▸ ALPL P05186 1/20 0.45
▸ ALPI P09923 1/20 0.45
▸ MMP1 P03956 1/20 0.43
▸ MMP2 P08253 1/20 0.43
▸ MMP9 P14780 1/20 0.43
▸ MMP8 P22894 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL929164 0.78 ALPL (0.53) CA1CA2CA9CA12CA14
SCHEMBL18263202 0.77 CA2 (0.49) CA1CA2CA9CA12CA14
SCHEMBL8623279 0.77 TDP1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL952515 0.77 KEAP1 (0.45) CA1CA2CA9CA12CA5A
SCHEMBL4538720 0.77 PLCG1 (0.45) CA1CA2CA9CA12CA14
SCHEMBL927603 0.77 ALDH1A1 (0.57) CA1CA2CA9CA12CA14
SCHEMBL4119819 0.76 TDP1 (0.48) CA1CA2CA9CA12CA7
SCHEMBL29657456 0.76 CA2 (0.55) CA1CA2CA9CA12CA14
SCHEMBL29488753 0.75 CA2 (0.59) CA1CA2CA9CA12CA14
SCHEMBL997443 0.75 CA2 (0.59) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114784378-A Electrolyte added with 4-nitrobenzenesulfonic acid pentafluorophenyl ester and homolog and lithium battery 湖南大学 2022-07-22 — — CN claimed
US-8816062-B2 Maleimide-furanyl compounds that can be used in a general method for preparing maleimide-oligonucleotide derivatives UNIVERSITAT DE BARCELONA (ES) 2014-08-26 — — US claimed
US-20130158248-A1 MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES UNIVERSITAT DE BARCELONA (ES) 2013-06-20 — — US claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-20250385912-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF THERAPEUTIC NANOPARTICLES DANTARI INC (US) 2025-12-18 — — US disclosed
US-20250152734-A1 USES AND FORMULATIONS OF CAMPTOTHECIN (CPT)-CONTAINING NANOPARTICLES DANTARI INC (US) 2025-05-15 — — US disclosed
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. (US) 2025-01-02 — — US disclosed
CN-119013047-A Use and formulation of Camptothecin (CPT) containing nanoparticles 丹塔里股份有限公司 2024-11-22 — — CN disclosed
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS INC. (US) 2024-07-16 — — US disclosed
WO-2024123732-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CANCER Dantari, Inc. (US) 2024-06-13 — — WO disclosed
EP-3265109-B1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-10-21 — — EP disclosed
US-20200308221-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-10-01 — — US disclosed
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2020-04-28 — — US disclosed
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2018-02-15 — — US disclosed
EP-3265109-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES Stealth BioTherapeutics Corp (MC) 2018-01-10 — — EP disclosed
CN-107530395-A Method for producing drug-related peptides 康德生物医疗技术公司 2018-01-02 — — CN disclosed
WO-2016144905-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2016-09-15 — — WO disclosed
US-8816062-B2 Maleimide-furanyl compounds that can be used in a general method for preparing maleimide-oligonucleotide derivatives UNIVERSITAT DE BARCELONA (ES) 2014-08-26 — — US disclosed
US-20130158248-A1 MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES UNIVERSITAT DE BARCELONA (ES) 2013-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD CA1 3147/4885CA2 2534/4885CA9 2504/4885
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD CA1 3147/4885CA2 2534/4885CA9 2504/4885
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 CA1 4068/4885CA2 4557/4885CA9 4739/4885
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD CA1 3147/4885CA2 2534/4885CA9 2504/4885
US-20200308221-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD CA1 3147/4885CA2 2534/4885CA9 2504/4885
US-20250152734-A1 USES AND FORMULATIONS OF CAMPTOTHECIN (CPT)-CONTAINING NANOPARTICLES MUC1, TOP2A, TOP1 CA1 748/4885CA2 2192/4885CA9 96/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 CA1 3497/4885CA2 4336/4885CA9 4794/4885
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD CA1 3147/4885CA2 2534/4885CA9 2504/4885
US-20130158248-A1 MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES NSUN2, POLL, NT5C3B CA1 1993/4885CA2 1246/4885CA9 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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