Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989267 | 0.91 | CCKAR (0.47) | PTGS2ALOX5PTGS1P2RX7MALT1 | |
| SCHEMBL9988639 | 0.91 | RXRA (0.46) | PTGS2EPHX2ALOX5PTGS1P2RX7 | |
| SCHEMBL9989581 | 0.90 | ILK (0.49) | PTGS2EPHX2ALOX5PTGS1SLC5A1 | |
| SCHEMBL9988720 | 0.89 | EPHX2 (0.46) | PTGS2EPHX2ALOX5PTGS1SLC5A1 | |
| SCHEMBL9988663 | 0.87 | PTGS2 (0.48) | PTGS2EPHX2ALOX5SLC5A1MALT1 | |
| SCHEMBL9989045 | 0.87 | RXRA (0.47) | PTGS2ALOX5PTGS1P2RX7MALT1 | |
| SCHEMBL9990073 | 0.86 | RXRA (0.48) | PTGS2ALOX5P2RX7MALT1RXRA | |
| SCHEMBL9990231 | 0.84 | RXRA (0.51) | PTGS2ALOX5P2RX7MALT1RXRA | |
| SCHEMBL9989582 | 0.82 | ALOX5 (0.53) | PTGS2ALOX5PTGS1P2RX7MALT1 | |
| SCHEMBL9988908 | 0.82 | MALT1 (0.46) | PTGS2EPHX2ALOX5SLC5A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |