Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989144 | 0.89 | SMN1; SMN2 (0.49) | ADORA2AADORA1MALT1MAPTSMN1; SMN2 | |
| SCHEMBL9988443 | 0.87 | NAMPT (0.44) | MALT1MAPTRXRARXRBRXRG | |
| SCHEMBL9988828 | 0.85 | MALT1 (0.45) | MALT1MAPTSMN1; SMN2ALOX5RXRA | |
| SCHEMBL9988868 | 0.84 | MALT1 (0.44) | MALT1MAPTALOX5RXRARXRB | |
| SCHEMBL9988364 | 0.84 | MALT1 (0.49) | MALT1ALOX5RXRARXRBRXRG | |
| SCHEMBL9988469 | 0.80 | RAB9A (0.40) | MAPTSMN1; SMN2ALOX5RXRARXRB | |
| SCHEMBL9988617 | 0.79 | MALT1 (0.43) | MALT1ALOX5 | |
| SCHEMBL9988457 | 0.78 | PTGS2 (0.44) | MAPTSMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9988522 | 0.78 | MALT1 (0.50) | ADORA2AADORA1MALT1SMN1; SMN2RXRA | |
| SCHEMBL9988491 | 0.77 | ALDH1A1 (0.49) | MAPTSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |