Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989823 | 0.90 | RXRA (0.40) | RAB9AKMT2AILKALOX5MAPT | |
| SCHEMBL9988576 | 0.88 | LMNA (0.47) | ILKALOX5MAPTALDH1A1KDM4E | |
| SCHEMBL9989270 | 0.86 | RXRA (0.45) | ILKALDH1A1KDM4ESCN9ARXRA | |
| SCHEMBL9988491 | 0.85 | ALDH1A1 (0.49) | RAB9AKMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL9988457 | 0.85 | PTGS2 (0.44) | KMT2ANPC1DGAT1SOAT1MAPT | |
| SCHEMBL9990127 | 0.84 | CA1 (0.44) | ILKSCN9ASLC5A1RXRARXRB | |
| SCHEMBL9988443 | 0.82 | NAMPT (0.44) | KMT2AILKMAPTALDH1A1TP53 | |
| SCHEMBL9989144 | 0.81 | SMN1; SMN2 (0.49) | KMT2AMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9988617 | 0.81 | MALT1 (0.43) | ALOX5FAAH | |
| SCHEMBL9988828 | 0.80 | MALT1 (0.45) | KMT2AALOX5MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |