Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989823 | 0.90 | RXRA (0.40) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9988576 | 0.88 | LMNA (0.47) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9988469 | 0.86 | RAB9A (0.40) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9990127 | 0.84 | CA1 (0.44) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9990151 | 0.81 | RXRA (0.52) | RXRARXRBRXRGMALT1CA1 | |
| SCHEMBL9988498 | 0.80 | RXRA (0.51) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9988373 | 0.80 | MALT1 (0.54) | RXRARXRBRXRGSCN9AKDM4E | |
| SCHEMBL9989347 | 0.80 | RXRA (0.49) | RXRARXRBRXRGILKMALT1 | |
| SCHEMBL9988500 | 0.80 | RXRA (0.47) | RXRARXRBRXRGSCN9AILK | |
| SCHEMBL9989059 | 0.78 | MALT1 (0.56) | RXRARXRBRXRGMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |