Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989681 | 0.88 | RXRA (0.48) | RXRARXRBRXRGTSHRMAPK1 | |
| SCHEMBL9990141 | 0.87 | RXRA (0.51) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9989656 | 0.86 | MALT1 (0.53) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9989046 | 0.86 | TP53 (0.50) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9988490 | 0.85 | LMNA (0.49) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9989011 | 0.84 | RXRA (0.48) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9990073 | 0.84 | RXRA (0.48) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9988536 | 0.84 | RXRA (0.48) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9988516 | 0.84 | RXRA (0.48) | LMNATP53RXRARXRBRXRG | |
| SCHEMBL9989578 | 0.84 | RXRA (0.47) | LMNATP53RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |