Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	ADRA2A known ✓	P08913	1/20	0.38

▸	ADRA2B known ✓	P18089	1/20	0.38

▸	ADRA2C known ✓	P18825	1/20	0.38

▸	ADRA1A known ✓	P35348	1/20	0.38

▸	ERN1	O75460	3/20	0.43

▸	CYP11B2	P19099	8/20	0.41

▸	CYP11B1	P15538	6/20	0.41

▸	ADORA2A	P29274	1/20	0.40

▸	ADORA1	P30542	1/20	0.40

▸	PRKCZ	Q05513	1/20	0.39

▸	CYP17A1	P05093	4/20	0.37

▸	KDM4E	B2RXH2	2/20	0.37

▸	ALDH1A1	P00352	2/20	0.37

▸	MAPT	P10636	1/20	0.37

▸	MAPKAPK2	P49137	1/20	0.35

▸	PARP1	P09874	1/20	0.35

▸	PRKCI	P41743	1/20	0.35

▸	PDE4B	Q07343	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	TDP1	Q9NUW8	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL31560042	1.00	ERN1 (0.43)	ERN1CYP11B2CYP11B1ADORA2AADORA1
Sulfuric Acid SCHEMBL31560041	1.00	ERN1 (0.43)	ERN1CYP11B2CYP11B1ADORA2AADORA1
SCHEMBL30605416	0.88	CYP11B2 (0.47)	ERN1CYP11B2CYP11B1ADORA2AADORA1
SCHEMBL18805059	0.88	CYP11B2 (0.47)	ERN1CYP11B2CYP11B1ADORA2AADORA1
SCHEMBL998807	0.88	CYP11B2 (0.47)	ERN1CYP11B2CYP11B1ADORA2AADORA1
SCHEMBL28481338	0.83	ALDH1A1 (0.52)	ERN1CYP11B2CYP11B1ADORA2AADORA1
SCHEMBL11139164	0.76	ALDH1A1 (0.42)	ERN1PRKCZADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL27568567	0.74	CTRB1 (0.42)	ERN1PRKCZALDH1A1HSD17B10
Sulfuric Acid SCHEMBL28657307	0.70	ROCK2 (0.45)	PRKCZKDM4EPRKCICYP3A4
SCHEMBL998049	0.70	ROCK2 (0.47)	PRKCZPRKCICYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-222788965-U	4-Fluoroisoquinoline sulfate impurity removing equipment	大连万福制药有限公司	2025-04-25	—	—	CN	claimed
CN-112047884-A	Synthesis method of 4-fluoroisoquinoline sulfate	沈阳市摩尔医药技术开发有限责任公司	2020-12-08	—	—	CN	claimed
EP-1852421-B1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	KOWA CO (JP)	2011-05-04	—	—	EP	claimed
US-7872136-B2	Process for production of 4-fluoroisoquinoline-5-sulfonyl halide or salt thereof	KOWA CO., LTD. (JP)	2011-01-18	—	—	US	claimed
US-20090209765-A1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	KOWA CO., LTD. (JP)	2009-08-20	—	—	US	claimed
EP-1852421-A1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	Kowa Company, Ltd. (JP)	2007-11-07	—	—	EP	claimed
CN-222788965-U	4-Fluoroisoquinoline sulfate impurity removing equipment	大连万福制药有限公司	2025-04-25	—	—	CN	disclosed
CN-222788965-U	4-Fluoroisoquinoline sulfate impurity removing equipment	大连万福制药有限公司	2025-04-25	—	—	CN	disclosed
CN-112047884-A	Synthesis method of 4-fluoroisoquinoline sulfate	沈阳市摩尔医药技术开发有限责任公司	2020-12-08	—	—	CN	disclosed
CN-112047884-A	Synthesis method of 4-fluoroisoquinoline sulfate	沈阳市摩尔医药技术开发有限责任公司	2020-12-08	—	—	CN	disclosed
CN-112047884-A	Synthesis method of 4-fluoroisoquinoline sulfate	沈阳市摩尔医药技术开发有限责任公司	2020-12-08	—	—	CN	disclosed
EP-1852421-B1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	KOWA CO (JP)	2011-05-04	—	—	EP	disclosed
US-7872136-B2	Process for production of 4-fluoroisoquinoline-5-sulfonyl halide or salt thereof	KOWA CO., LTD. (JP)	2011-01-18	—	—	US	disclosed
US-20090209765-A1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	KOWA CO., LTD. (JP)	2009-08-20	—	—	US	disclosed
EP-1852421-A1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	Kowa Company, Ltd. (JP)	2007-11-07	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20090209765-A1	PROCESS FOR PRODUCTION OF 4-FLUOROISOQUINOLINE-5-SULFONYL HALIDE OR SALT THEREOF	SALL4, STS, SFPQ	ADRA2A 3883/4885ADRA2B 3879/4885ADRA2C 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.