Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9994209 | 0.89 | NAMPT (0.44) | NAMPTGPR119PKMSCD5 | |
| SCHEMBL9994834 | 0.87 | NAMPT (0.38) | NAMPT | |
| SCHEMBL9994673 | 0.85 | NAMPT (0.47) | NAMPTGPR119PKMSCD5 | |
| SCHEMBL9993019 | 0.83 | SCD5 (0.45) | NAMPTGPR119PKMSCD5 | |
| SCHEMBL9994514 | 0.79 | NAMPT (0.44) | NAMPTGPR119PKMSCD5 | |
| SCHEMBL29179904 | 0.79 | NAMPT (0.55) | NAMPTGPR119PKM | |
| SCHEMBL346185 | 0.76 | PKM (0.42) | NAMPTPKMSCD5 | |
| SCHEMBL9993013 | 0.75 | NAMPT (0.46) | NAMPTGPR119PKMSCD5 | |
| SCHEMBL9993034 | 0.75 | NAMPT (0.36) | NAMPT | |
| SCHEMBL345715 | 0.75 | KDM4E (0.46) | NAMPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889702-B2 | Derivatives of azaspiranyl-alkylcarbamates of 5-member heterocyclic compounds, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-11-18 | — | — | US | disclosed |
| US-20110319381-A1 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319381-A1 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | PRMT9, IDH3B, DHFR | NAMPT 54/4885GPR119 1390/4885PKM 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.