Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498859 | 0.87 | MEN1 (0.44) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL8498725 | 0.85 | LTA4H (0.55) | MEN1KMT2ATDP1MAPTDRD4 | |
| SCHEMBL22564629 | 0.81 | LMNA (0.45) | MEN1KMT2AMAPTCHRM2KDM4E | |
| SCHEMBL9965802 | 0.80 | MEN1 (0.64) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL11370850 | 0.79 | MEN1 (0.70) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL22014817 | 0.79 | CYP1A2 (0.60) | MEN1KMT2ATDP1MAOAMAPT | |
| Hydrochloric Acid SCHEMBL4349681 | 0.78 | MEN1 (0.61) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL141336 | 0.77 | MEN1 (0.73) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL5764 | 0.76 | MEN1 (1.00) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL23791770 | 0.76 | MEN1 (0.64) | MEN1KMT2ATDP1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10018623-B1 | Molecular probes for ascorbate detection and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2018-07-10 | — | — | US | disclosed |
| US-20110294992-A1 | METAL RESPONSIVE MRI-AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294992-A1 | METAL RESPONSIVE MRI-AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294992-A1 | METAL RESPONSIVE MRI-AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10018623-B1 | Molecular probes for ascorbate detection and methods of use | PROC, CALCOCO2, CACYBP | MEN1 3175/4885KMT2A 4244/4885TDP1 2677/4885 |
| US-20110294992-A1 | METAL RESPONSIVE MRI-AGENTS | SLC11A2, TRIM59, AIFM2 | MEN1 69/4885KMT2A 680/4885TDP1 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.