Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801696 | 0.86 | PPARA (0.54) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL8471261 | 0.81 | SLC6A4 (0.58) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL9995320 | 0.78 | SLC6A4 (0.52) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL872624 | 0.77 | SLC6A4 (0.53) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL872958 | 0.76 | CXCL8 (0.67) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL1146416 | 0.75 | HTR2A (0.54) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL12361548 | 0.75 | SLC6A4 (0.54) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| Ammonia Solution, Strong SCHEMBL872909 | 0.75 | CHRM1 (0.65) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL13474499 | 0.74 | SLC6A4 (0.53) | PPARASLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL27912315 | 0.74 | SLC6A2 (0.56) | PPARASLC6A4SLC6A2SLC6A3SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779161-B2 | Asenapine maleate | DR. REDDY'S LABORATORIES LIMITED (IN) | 2014-07-15 | — | — | US | disclosed |
| US-20130211099-A1 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2582704-A2 | ASENAPINE MALEATE | Dr. Reddy's Laboratories Ltd. (IN) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159903-A2 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130211099-A1 | ASENAPINE MALEATE | CYP3A5, AANAT, ADRA2C | PPARA 3069/4885SLC6A4 17/4885SLC6A2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.