Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999563 | 0.82 | FAAH (0.60) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| SCHEMBL13064454 | 0.80 | CA1 (0.63) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL1056876 | 0.80 | FAAH (0.58) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| SCHEMBL19941500 | 0.78 | CA12 (0.55) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| SCHEMBL77781 | 0.78 | F2 (1.00) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL6425431 | 0.77 | F2 (1.00) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL25973 | 0.77 | F2 (1.00) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| Phenethylamine SCHEMBL77780 | 0.76 | HTR2A (0.73) | F2TMPRSS4CYP1A2TP53CYP2D6 | |
| SCHEMBL224548 | 0.75 | TAAR1 (0.72) | CYP1A2CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL723369 | 0.75 | F2 (0.92) | F2TMPRSS4CYP1A2TP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572185-A4 | LIPOXYGENASE INHIBITORS AS HYPOLIPIDEMIC AND ANTI-HYPERTENSIVE AGENTS | INSMED INC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1572185-A1 | LIPOXYGENASE INHIBITORS AS HYPOLIPIDEMIC AND ANTI-HYPERTENSIVE AGENTS | Insmed Incorporated (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20040198800-A1 | Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents | INSMED INCORPORATED | 2004-10-07 | — | — | US | disclosed |
| WO-2004058240-A1 | LIPOXYGENASE INHIBITORS AS HYPOLIPIDEMIC AND ANTI-HYPERTENSIVE AGENTS | INSMED INCORPORATED (US) | 2004-07-15 | — | — | WO | disclosed |
| EP-0759066-B1 | PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF | DEGUSSA (DE) | 2001-06-27 | — | — | EP | disclosed |
| EP-1043394-A2 | Combination containing prostate-specific-antigen (PSA) | SERATEC Gesellschaft für Biotechnologie mbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| US-5985632-A | Peptide amidase from xanthomonas | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198800-A1 | Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents | ALOX5, ALOX15, ALOX15B | F2 1916/4885TMPRSS4 1428/4885CYP1A2 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.