Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | RPA1 | P27694 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | WDR5 | P61964 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997386 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10GFERWDR5 | |
| SCHEMBL11665915 | 0.79 | BRD4 (0.57) | ALDH1A1HPGDHSD17B10RPA1GFER | |
| SCHEMBL9997031 | 0.77 | ALDH1A1 (0.73) | ALDH1A1HPGDHSD17B10RPA1GFER | |
| SCHEMBL9997964 | 0.76 | FABP4 (0.60) | ALDH1A1HPGDHSD17B10WDR5KDM4E | |
| SCHEMBL11665908 | 0.76 | BRD4 (0.57) | ALDH1A1HPGDHSD17B10RPA1GFER | |
| SCHEMBL2888830 | 0.76 | KDM1A (0.54) | ALDH1A1KDM4EPOLBMCL1BCL2L1 | |
| SCHEMBL30858466 | 0.74 | KMT2A (0.53) | ALDH1A1WDR5POLBKMT2AMEN1 | |
| SCHEMBL28637555 | 0.73 | KMT2A (0.58) | ALDH1A1HPGDHSD17B10KDM4EPOLB | |
| SCHEMBL9997180 | 0.72 | PTK2B (0.51) | ALDH1A1HPGDHSD17B10MCL1BCL2L1 | |
| SCHEMBL13870868 | 0.72 | RPA1 (1.00) | ALDH1A1HPGDRPA1GFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |