Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637555 | 0.82 | KMT2A (0.58) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL9996881 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL9997384 | 0.81 | LMNA (0.67) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL9997012 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL9999225 | 0.78 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL9997303 | 0.77 | GLO1 (0.54) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL6079716 | 0.77 | MEN1 (0.53) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL28637411 | 0.77 | ACLY (0.55) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL9997531 | 0.77 | KMT2A (0.66) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL2888830 | 0.76 | KDM1A (0.54) | ALDH1A1MEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |