SCHEMBL999756

SCHEMBL999756

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nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 19/20 0.61
CTSK P43235 16/20 0.61
CTSL P07711 2/20 0.58
CTSB P07858 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17708331 1.00 CTSS (0.61) CTSSCTSKCTSLCTSB
SCHEMBL999757 1.00 CTSS (0.61) CTSSCTSKCTSLCTSB
SCHEMBL1952503 1.00 CTSS (0.61) CTSSCTSKCTSLCTSB
SCHEMBL29524801 0.87 CTSS (0.57) CTSSCTSKCTSLCTSB
SCHEMBL29063337 0.86 CTSS (0.56) CTSSCTSKCTSLCTSB
SCHEMBL29046818 0.86 CTSS (0.56) CTSSCTSKCTSLCTSB
SCHEMBL28752529 0.86 CTSS (0.56) CTSSCTSKCTSLCTSB
SCHEMBL1645984 0.85 CTSS (0.56) CTSSCTSKCTSLCTSB
SCHEMBL1645980 0.85 CTSS (0.56) CTSSCTSKCTSLCTSB
SCHEMBL13318956 0.84 CTSS (0.59) CTSSCTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735451-A1 SUBSTITUTED CONDENSED TRICYCLIC AMINE COMPOUNDS AND USES THEREOF AS RAS INHIBITORS Kumquat Biosciences Inc. (US) 2026-05-06 EP disclosed
US-20250263459-A1 STABILIZED PACAP PEPTIDE SENJU PHARMACEUTICAL CO., LTD. (JP) 2025-08-21 US disclosed
US-20250243238-A1 TETRAZINE AMINO ACIDS AND METHODS FOR THEIR PRODUCTION AND USE OREGON STATE UNIVERSITY (US) 2025-07-31 US disclosed
WO-2025106386-A1 A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed
US-20250152658-A1 CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-15 US disclosed
CN-116284185-B Nucleotide analogs and their use in sequencing 深圳赛陆医疗科技有限公司 2025-04-08 CN disclosed
WO-2025007000-A1 SUBSTITUTED CONDENSED TRICYCLIC AMINE COMPOUNDS AND USES THEREOF AS RAS INHIBITORS KUMQUAT BIOSCIENCES INC. (US) 2025-01-02 WO disclosed
US-20240383915-A1 OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER GENENTECH, INC. (US) 2024-11-21 US disclosed
EP-3974027-B1 STABILIZED PACAP PEPTIDE SENJU PHARMA CO (JP) 2024-10-23 EP disclosed
EP-4320132-A1 OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER Genentech, Inc. (US) 2024-02-14 EP disclosed
WO-2005000878-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2005-01-06 WO disclosed
WO-2004063198-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2004-07-29 WO disclosed
EP-0998488-B1 POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-03-17 EP disclosed
US-6423869-B1 BACTERICIDES, ANTIULCER AGENTS TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2002-07-23 US disclosed
EP-0998488-A1 POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY Takeda Chemical Industries, Ltd. (JP) 2000-05-10 EP disclosed
WO-1999002549-A1 POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-01-21 WO disclosed
US-5648337-A Antiherpes pentapeptides BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1997-07-15 US disclosed
EP-0408973-B1 Antiherpes pentapeptides BIO MEGA BOEHRINGER INGELHEIM (CA) 1996-10-23 EP disclosed
EP-0408973-A1 Antiherpes pentapeptides BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-01-23 EP disclosed
EP-0405506-A1 Tetrapeptide type-B CCK receptor ligands ABBOTT LABORATORIES (US) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263459-A1 STABILIZED PACAP PEPTIDE GRIK5, VGF, NPY5R CTSS 1454/4885CTSK 302/4885CTSL 962/4885
US-20250243238-A1 TETRAZINE AMINO ACIDS AND METHODS FOR THEIR PRODUCTION AND USE DNPEP, AADAT, NPEPPS CTSS 2935/4885CTSK 2227/4885CTSL 1093/4885
US-20240383915-A1 OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER OXA1L, GRIK4, GRIK5 CTSS 3970/4885CTSK 3197/4885CTSL 2939/4885
US-20250152658-A1 CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA IL1R1, IL1A, IL1B CTSS 1403/4885CTSK 1280/4885CTSL 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.