SCHEMBL999924

SCHEMBL999924

O=C(O)CN1CCN(CC(=O)O)CC(Cc2ccc(N=C=S)cc2)N(CC(=O)O)CC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
FOLH1 Q04609 2/20 0.43
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX12 P18054 1/20 0.38
OPRD1 P41143 1/20 0.37
P2RY6 Q15077 1/20 0.36
CHRM1 P11229 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5864681 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL16925973 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL210579 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL27143361 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL1079076 1.00 GRIN1 (0.48) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL16925972 0.96 GRIN1 (0.47) GRIN1GRIN2AGRIN2BFOLH1TP53
SCHEMBL16922664 0.95 GRIN1 (0.45) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL16922665 0.95 GRIN1 (0.45) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL436048 0.95 GRIN1 (0.45) GRIN1GRIN2AGRIN2BFOLH1HSD17B10
SCHEMBL24220975 0.94 GRIN1 (0.44) GRIN1GRIN2AGRIN2BFOLH1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-12-04 US claimed
US-20250276071-A1 NANOPLATFORM FOR TARGETING INFLAMMATORY MACROPHAGES, AND COMPOSITION CONTAINING SAME FOR PREVENTING OR TREATING INFLAMMATORY DISEASES CLICHEMBIO, INC (KR) 2025-09-04 US claimed
EP-4585209-A1 NANOPLATFORM FOR TARGETING INFLAMMATORY MACROPHAGES, AND COMPOSITION CONTAINING SAME FOR PREVENTING OR TREATING INFLAMMATORY DISEASES Clichembio, Inc. (KR) 2025-07-16 EP claimed
WO-2024177490-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME 서울대학교산학협력단 2024-08-29 WO claimed
US-20240199722-A1 NANOPLATFORM FOR TARGETING MACROPHAGE AND COMPOSITION FOR PREVENTION OR TREATMENT OF METASTATIC CANCER SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-06-20 US claimed
EP-4380633-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF Rayzebio, Inc. (US) 2024-06-12 EP claimed
WO-2024112181-A1 NANOPLATFORM FOR TARGETING INFLAMMATORY MACROPHAGES, AND COMPOSITION CONTAINING SAME FOR PREVENTING OR TREATING INFLAMMATORY DISEASES (주)클리켐바이오 2024-05-30 WO claimed
US-20240123098-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. 2024-04-18 US claimed
US-11819556-B2 Stabilized compositions of radionuclides and uses thereof RAYZEBIO, INC. (US) 2023-11-21 US claimed
CN-117065056-A Radionuclide-labeled 1B50-1 antibody and preparation method and application thereof 北京肿瘤医院(北京大学肿瘤医院) 2023-11-17 CN claimed
US-20220175975-A1 HER3 Peptides for Imaging and Radiotherapy THE GENERAL HOSPITAL CORPORATION 2022-06-09 US claimed
US-11241511-B2 HER3 peptides for imaging and radiotherapy THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
US-20220031873-A1 Multi-Modal Contrast Agent For Medical Imaging BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2022-02-03 US claimed
CN-113444146-A Targeted fibroblast activation protein probe, preparation method and application thereof in preparation of PET (polyethylene terephthalate) imaging agent 南方医科大学南方医院 2021-09-28 CN claimed
CN-112142739-A Folic acid receptor-targeted radioactive folic acid derivative and preparation method and application thereof 上海交通大学医学院附属仁济医院 2020-12-29 CN claimed
US-20200121814-A1 HER3 Peptides for Imaging and Radiotherapy UNITED STATES GOVERNMENT 2020-04-23 US claimed
US-20190321495-A1 COMPOSITIONS AND METHODS OF TREATING MELANOMA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2019-10-24 US claimed
US-10130725-B2 Method for labeling exosomes with radioactive substance and use thereof SNU R&DB FOUNDATION (KR) 2018-11-20 US claimed
WO-2018126183-A2 HER3 PEPTIDES FOR IMAGING AND RADIOTHERAPY THE GENERAL HOSPITAL CORPORATION (US) 2018-07-05 WO claimed
US-20170143856-A1 METHOD FOR LABELING EXOSOMES WITH RADIOACTIVE SUBSTANCE AND USE THEREOF SNU R&DB FOUNDATION (KR) 2017-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199722-A1 NANOPLATFORM FOR TARGETING MACROPHAGE AND COMPOSITION FOR PREVENTION OR TREATMENT OF METASTATIC CANCER SIGLEC9, B3GNT2, NEU3 GRIN1 3195/4885GRIN2A 3330/4885GRIN2B 3594/4885
US-20250276071-A1 NANOPLATFORM FOR TARGETING INFLAMMATORY MACROPHAGES, AND COMPOSITION CONTAINING SAME FOR PREVENTING OR TREATING INFLAMMATORY DISEASES GLS, TNF, ARG2 GRIN1 864/4885GRIN2A 1216/4885GRIN2B 1915/4885
US-11819556-B2 Stabilized compositions of radionuclides and uses thereof TFRC, SLC39A14, EGFR GRIN1 3937/4885GRIN2A 4103/4885GRIN2B 4456/4885
US-20220175975-A1 HER3 Peptides for Imaging and Radiotherapy ERBB3, EGFR, NGLY1 GRIN1 2533/4885GRIN2A 3766/4885GRIN2B 2840/4885
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME ALB, TNNC1, MYOF GRIN1 4527/4885GRIN2A 4636/4885GRIN2B 4705/4885
US-11241511-B2 HER3 peptides for imaging and radiotherapy ERBB3, EGFR, NGLY1 GRIN1 2533/4885GRIN2A 3766/4885GRIN2B 2840/4885
US-20200121814-A1 HER3 Peptides for Imaging and Radiotherapy ERBB3, EGFR, NGLY1 GRIN1 2533/4885GRIN2A 3766/4885GRIN2B 2840/4885
US-20190321495-A1 COMPOSITIONS AND METHODS OF TREATING MELANOMA MC1R, TIE1, MKI67 GRIN1 3696/4885GRIN2A 4714/4885GRIN2B 4645/4885
US-20240123098-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF TFRC, SLC39A14, EGFR GRIN1 3937/4885GRIN2A 4103/4885GRIN2B 4456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.