SCHEMBL9999613

SCHEMBL9999613

Cc1ccc(-c2nc3ccccn3c2CN)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.66
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 3/20 0.54
POLB P06746 1/20 0.54
HTT P42858 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MAPK1 P28482 1/20 0.52
MAPT P10636 2/20 0.51
KCNK3 O14649 4/20 0.51
KCNK9 Q9NPC2 4/20 0.51
ADORA1 P30542 1/20 0.50
TP53 P04637 1/20 0.49
SLC2A1 P11166 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28372805 0.89 NPC1 (0.56) DPP4NPC1RAB9AALDH1A1KDM4E
SCHEMBL18978250 0.87 NPC1 (0.59) DPP4NPC1RAB9AALDH1A1KDM4E
SCHEMBL1431023 0.85 KDM4E (0.62) DPP4NPC1RAB9AKDM4EPOLB
SCHEMBL1431043 0.85 KDM4E (0.69) DPP4NPC1RAB9AKDM4EPOLB
SCHEMBL1691474 0.85 ALDH1A1 (0.58) NPC1RAB9AALDH1A1KDM4EPOLB
Hydrochloric Acid SCHEMBL1430695 0.84 NPC1 (0.57) NPC1RAB9AALDH1A1KDM4EPOLB
SCHEMBL4253068 0.82 GABRA1 (0.61) ALDH1A1KDM4ESMN1; SMN2MAPTTP53
SCHEMBL8091720 0.82 NPC1 (0.54) DPP4NPC1RAB9AALDH1A1KDM4E
SCHEMBL5566700 0.82 ALDH1A1 (0.65) NPC1RAB9AALDH1A1KDM4EPOLB
SCHEMBL28615473 0.81 NPC1 (0.60) NPC1RAB9AALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11292878-B2 Poly(L-lysine isolphthalamide) (PLP) polymers with hydrophobic pendant chains Chen, Rongjun (GB) 2022-04-05 US disclosed
EP-3484521-B1 POLY(L-LYSINE ISOPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS ALPHACELLS BIOTECHNOLOGIES LTD (GB) 2021-04-07 EP disclosed
US-20190248956-A1 POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS IMPERIAL INNOVATIONS LIMITED (GB) 2019-08-15 US disclosed
WO-2012014898-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2012-02-02 WO disclosed
WO-2011132751-A1 LIQUID-CRYSTAL ALIGNMENT AGENT, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2011-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248956-A1 POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS PLP2, LNPEP, PLPBP DPP4 994/4885NPC1 1119/4885RAB9A 4373/4885
US-11292878-B2 Poly(L-lysine isolphthalamide) (PLP) polymers with hydrophobic pendant chains PLP2, LNPEP, PLPBP DPP4 994/4885NPC1 1119/4885RAB9A 4373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.