Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 7/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 7/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 7/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 7/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 7/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 7/20 | 0.40 |
| ▸ | CACNG1 | Q06432 | 7/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 7/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618558 | 0.90 | HPGD (0.39) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL618531 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL619405 | 0.88 | GABRP (0.45) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL620595 | 0.87 | ACHE (0.44) | KDM4EALDH1A1HPGDACHECACNB4 | |
| SCHEMBL620400 | 0.87 | ACHE (0.44) | KDM4EALDH1A1HPGDACHECACNB4 | |
| SCHEMBL17730201 | 0.85 | GABRP (0.44) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL21267928 | 0.84 | GABRP (0.44) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL618842 | 0.84 | TSHR (0.39) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL28448948 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAAACHE | |
| SCHEMBL28454801 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2015-09-24 | — | — | US | disclosed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | disclosed |
| US-9049878-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9000054-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | KDM4E 476/4885ALDH1A1 3324/4885HPGD 3816/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | KDM4E 476/4885ALDH1A1 3324/4885HPGD 3816/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | KDM4E 476/4885ALDH1A1 3324/4885HPGD 3816/4885 |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885ALDH1A1 664/4885HPGD 2448/4885 |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885ALDH1A1 664/4885HPGD 2448/4885 |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885ALDH1A1 664/4885HPGD 2448/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | KDM4E 476/4885ALDH1A1 3324/4885HPGD 3816/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | KDM4E 476/4885ALDH1A1 3324/4885HPGD 3816/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885ALDH1A1 664/4885HPGD 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.