CACNG6

Voltage-dependent calcium channel gamma-6 sub · Q9BXT2 · CACNG6 on Sugi Atlas →

5,953 patent compounds predicted against CACNG6, 2,307 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL116362 SCHEMBL116362 0.45 11/20
SCHEMBL6121858 SCHEMBL6121858 0.52 9/20
SCHEMBL2585915 SCHEMBL2585915 0.51 8/20
SCHEMBL3354274 SCHEMBL3354274 0.62 7/20
SCHEMBL3357851 SCHEMBL3357851 0.54 7/20
SCHEMBL4750473 SCHEMBL4750473 0.52 7/20
SCHEMBL3350921 SCHEMBL3350921 0.49 7/20
SCHEMBL619154 SCHEMBL619154 0.41 7/20
SCHEMBL620978 SCHEMBL620978 0.40 7/20
SCHEMBL621013 SCHEMBL621013 0.40 7/20
SCHEMBL5428566 SCHEMBL5428566 0.52 6/20
SCHEMBL621555 SCHEMBL621555 0.39 6/20
SCHEMBL617973 SCHEMBL617973 0.38 6/20
SCHEMBL7053553 SCHEMBL7053553 0.62 5/20
SCHEMBL4405461 SCHEMBL4405461 0.55 5/20
SCHEMBL4399845 SCHEMBL4399845 0.54 5/20
SCHEMBL4967687 SCHEMBL4967687 0.51 5/20
SCHEMBL1810921 SCHEMBL1810921 0.51 5/20
SCHEMBL4399843 SCHEMBL4399843 0.50 5/20
SCHEMBL3477582 SCHEMBL3477582 0.47 5/20

Clinical trials — most relevant to CACNG6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination PHASE4UNKNOWN
Comparative Study of Dietary and Immunological Management of Refractory Epilepsy in Children PHASE4UNKNOWN
Role of Intralipid in Management of Organophosphorus Poisoning PHASE2/PHASE3WITHDRAWN
The Re-Prosper HF Study PHASE2/PHASE3COMPLETED
Population Pharmacokinetic-pharmacodynamic (PK-PD) Modeling of Co-administered Gabapentin in Neuropathic Pain PHASE2COMPLETED
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients PHASE2WITHDRAWN
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Trauma Patients PHASE2WITHDRAWN
A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome PHASE1/PHASE2NOT_YET_RECRUITING
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease PHASE2COMPLETED
Physiologic Effects of Topiramate on Cognition PHASE1COMPLETED
Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases nanUNKNOWN
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption nanCOMPLETED
Factors Affecting Salt Intake in Young Adults nanUNKNOWN
ST-segment Elevation as an AF Endophenotype nanCOMPLETED
Sodium Channel Splicing in Heart Failure Trial nanCOMPLETED
Evaluation of A Clinical Diagnostic Test for CRDS nanRECRUITING
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY) nanCOMPLETED
Multicenter Study of Patients With SHANK3 Mutations: Identification of Genes Modificators in Phelan-McDermid Syndrome (EUQ13) nanNOT_YET_RECRUITING
Exploring the Genetics of Neuropathic Pain nanRECRUITING
Neurogenetic And Hemodynamic Of Migraine Aura And Pfo nanRECRUITING
Neurogenic Mechanisms in Burning Mouth Syndrome nanCOMPLETED
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development nanRECRUITING
Rolandic Epilepsy Genomewide Association International Study nanCOMPLETED
MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants nanRECRUITING
Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study nanUNKNOWN
The Influence of Genetic Predisposition on Outcome After Catheter Ablation of Atrial Fibrillation. nanUNKNOWN
Clinical-genetic Investigations in Children With Early Infantile Epilepsies nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CACNG6 binder may also engage these)

ProteinNameSimilarity
Q8VHW7 0.990 Q8VHW7 →
Q8VHW3 0.987 Q8VHW3 →
Q9CZ16 0.979 Q9CZ16 →
Q8NBL3 0.974 Q8NBL3 →
Q68FV0 0.973 Q68FV0 →
Q9D563 0.972 Q9D563 →
B3SHH9 0.971 B3SHH9 →
F6V1J6 0.968 F6V1J6 →
Q08DE1 0.968 Q08DE1 →
CACNG1 Voltage-dependent calcium channel gamma-1 sub 0.960 landscape →
Q5XGU1 0.957 Q5XGU1 →
Q14714 0.955 Q14714 →
P82352 0.954 P82352 →
O70578 0.954 O70578 →
Q2MJQ7 0.953 Q2MJQ7 →
P19518 0.953 P19518 →
Q08CE6 0.952 Q08CE6 →
Q969K7 0.952 Q969K7 →
P97707 0.950 P97707 →
Q3ZCD2 0.950 Q3ZCD2 →
Q62147 0.949 Q62147 →
Q4R4Z3 0.942 Q4R4Z3 →
Q9BSN7 0.942 Q9BSN7 →
B2RVY9 0.942 B2RVY9 →
A4IF75 0.940 A4IF75 →
P51810 0.940 P51810 →
Q6UXU4 0.940 Q6UXU4 →
Q5RDV7 0.940 Q5RDV7 →
Q9NY35 0.940 Q9NY35 →
Q9CQX5 0.939 Q9CQX5 →