Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483445 | 0.94 | GSTK1 (0.74) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL28749288 | 0.94 | GSTK1 (0.74) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL30190004 | 0.88 | GSTK1 (0.71) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL30504236 | 0.88 | GSTK1 (0.71) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL24638178 | 0.87 | AKR1B1 (0.61) | GSTK1SLC22A6TSHRKMT2AHDAC11 | |
| SCHEMBL28386070 | 0.87 | AKR1B1 (0.54) | GSTK1SLC22A6TSHRHDAC3KMT2A | |
| SCHEMBL2998661 | 0.87 | AKR1B1 (0.54) | GSTK1SLC22A6TSHRHDAC3KMT2A | |
| SCHEMBL17188267 | 0.86 | GSTK1 (0.58) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL11619149 | 0.86 | GSTK1 (0.64) | GSTK1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL754548 | 0.86 | GSTK1 (0.58) | GSTK1LMNASLC22A6TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173630-B2 | Multipodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | claimed |
| EP-4319823-A1 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | North Carolina State University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| US-9822123-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2017-11-21 | — | — | US | disclosed |
| US-7582751-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090198049-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-30 | — | — | US | disclosed |
| US-7534807-B2 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-17 | — | — | US | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | PPOX, DLD, PYCR1 | GSTK1 2427/4885LMNA 1483/4885SLC22A6 2052/4885 |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | GSTK1 1217/4885LMNA 2153/4885SLC22A6 1847/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | GSTK1 1108/4885LMNA 2225/4885SLC22A6 3563/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | GSTK1 508/4885LMNA 2242/4885SLC22A6 408/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | GSTK1 2352/4885LMNA 3706/4885SLC22A6 612/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | GSTK1 508/4885LMNA 2242/4885SLC22A6 408/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | GSTK1 1100/4885LMNA 2813/4885SLC22A6 1008/4885 |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | GSTK1 521/4885LMNA 1601/4885SLC22A6 2955/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | GSTK1 1217/4885LMNA 2153/4885SLC22A6 1847/4885 |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, HMBS, CYC1 | GSTK1 396/4885LMNA 1169/4885SLC22A6 3498/4885 |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | DNMT1, TET1, SOD1 | GSTK1 220/4885LMNA 4719/4885SLC22A6 3253/4885 |
| US-20090198049-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | PPOX, HMBS, CYC1 | GSTK1 396/4885LMNA 1169/4885SLC22A6 3498/4885 |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | GSTK1 1217/4885LMNA 2153/4885SLC22A6 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.