Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | S100B | P04271 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | LGMN | Q99538 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533602 | 0.91 | LGMN (0.87) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL3536844 | 0.90 | LGMN (0.87) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL3533660 | 0.90 | MAPT (0.87) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL31000427 | 0.90 | MAPT (0.87) | ALDH1A1HTTMAPTGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL3539659 | 0.88 | MAPT (0.84) | ALDH1A1HTTMAPTGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL30501445 | 0.88 | LGMN (0.84) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL9073400 | 0.88 | MAPT (0.77) | ALDH1A1HTTMAPTGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL20598232 | 0.87 | LGMN (0.82) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL23043599 | 0.84 | S100B (1.00) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL8074303 | 0.83 | MAPT (0.71) | ALDH1A1HTTMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |
| EP-1807407-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | claimed |
| US-20060100201-A1 | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-11 | — | — | US | claimed |
| WO-2006047504-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | claimed |
| CN-113646899-B | n-type semiconductor element, method for manufacturing n-type semiconductor element, wireless communication device, and commodity tag | 东丽株式会社 | 2024-03-12 | — | — | CN | disclosed |
| US-11535597-B2 | Photoreactive ligands and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-27 | — | — | US | disclosed |
| CN-113646899-A | n-type semiconductor element, method for manufacturing n-type semiconductor element, wireless communication device, and merchandise tag | 东丽株式会社 | 2021-11-12 | — | — | CN | disclosed |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2020-03-05 | — | — | US | disclosed |
| US-7718673-B2 | Isonipecotamides for the treatment of integrin-mediated disorders | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | disclosed |
| CN-101084208-A | Aromatic amides as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-05 | — | — | CN | disclosed |
| WO-2006047504-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
| EP-1133489-B9 | ISONIPECOTAMIDES FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2006-05-03 | — | — | EP | disclosed |
| EP-1133489-B1 | ISONIPECOTAMIDES FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1533310-A1 | Isonipecotamides for the treatment of integrin-mediated disorders | Ortho-McNeil Pharmaceutical, Inc. (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20030181440-A1 | Isonipecotamides for the treatment of integrin-mediated disorders | COSTANZO MICHAEL J (US) | 2003-09-25 | — | — | US | disclosed |
| CN-1352641-A | Isopiperidinecarboxamides for the treatment of integrin-mediated disorders | ORTHO MCNEIL PHARM INC (US) | 2002-06-05 | — | — | CN | disclosed |
| EP-1133489-A1 | ISONIPECOTAMIDES FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2001023376-A1 | ISONIPECOTAMIDES FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535597-B2 | Photoreactive ligands and uses thereof | CLTB, CRYAB, CRYAA | ALDH1A1 2216/4885HTT 3816/4885MAPT 3004/4885 |
| US-20060100201-A1 | Inhibitors of c-fms kinase | MUSK, FLT3, FES | ALDH1A1 4796/4885HTT 1421/4885MAPT 159/4885 |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | CLTB, CRYAB, CRYAA | ALDH1A1 2216/4885HTT 3816/4885MAPT 3004/4885 |
| US-20030181440-A1 | Isonipecotamides for the treatment of integrin-mediated disorders | ITGB2, ITGA1, ITGB1 | ALDH1A1 428/4885HTT 3866/4885MAPT 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.