Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.62 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 8/20 | 0.61 |
| ▸ | PPARA | Q07869 | 6/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | CPA1 | P15085 | 3/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392827 | 0.86 | CYP1A2 (0.70) | SRRPTGS1LDHACPA1CYP1A2 | |
| SCHEMBL30877184 | 0.86 | LDHA (0.68) | PPARGLMNATSHRPTGS1LDHA | |
| Hydrochloric Acid SCHEMBL7304155 | 0.84 | CYP1A2 (0.67) | SRRPTGS1LDHACPA1CYP1A2 | |
| SCHEMBL28314499 | 0.84 | CYP1A2 (0.67) | SRRPTGS1LDHACPA1CYP1A2 | |
| SCHEMBL27876635 | 0.84 | CYP1A2 (0.67) | SRRPTGS1LDHACPA1CYP1A2 | |
| SCHEMBL28377626 | 0.84 | CYP1A2 (0.67) | SRRPTGS1LDHACPA1CYP1A2 | |
| SCHEMBL23512609 | 0.83 | LDHA (0.56) | SRRPSAT1PPARGPPARALMNA | |
| SCHEMBL14540332 | 0.83 | SLC1A3 (0.61) | SRRPSAT1PPARGPPARAFFAR1 | |
| SCHEMBL3353929 | 0.83 | MME (0.60) | SRRPSAT1PPARGPPARAFFAR1 | |
| SCHEMBL6382096 | 0.82 | SRR (0.57) | SRRPSAT1PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183909-B2 | Process for preparation of N-Boc biphenyl alaninol | CHIRAL QUEST (SUZHOU) CO., LTD. (CN) | 2019-01-22 | — | — | US | disclosed |
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2018-11-20 | — | — | US | disclosed |
| EP-2172450-B9 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-10-08 | — | — | EP | disclosed |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS (FR) | 2014-06-12 | — | — | US | disclosed |
| US-8703747-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | PHARMALEADS (FR) | 2014-04-22 | — | — | US | disclosed |
| EP-2172450-B1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | disclosed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | disclosed |
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS | 2011-05-26 | — | — | US | disclosed |
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2002-11-14 | — | — | US | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0566157-A1 | Neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4801609-A | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0254032-A2 | Neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1988-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183909-B2 | Process for preparation of N-Boc biphenyl alaninol | RABL6, PF4, SPIN4 | SRR 106/4885PSAT1 1534/4885PPARG 782/4885 |
| US-20110124601-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | SRR 388/4885PSAT1 3210/4885PPARG 3229/4885 |
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | MMP9, MMP3, MMP14 | SRR 288/4885PSAT1 366/4885PPARG 3001/4885 |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | MMP3, MMP11, TIMP3 | SRR 1832/4885PSAT1 757/4885PPARG 4639/4885 |
| US-10131681-B2 | Aminophosphinic derivatives that can be used in the treatment of pain | OPRM1, HRH3, HRH4 | SRR 400/4885PSAT1 3231/4885PPARG 3173/4885 |
| US-20140161839-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | OPRM1, HRH3, HRH4 | SRR 400/4885PSAT1 3231/4885PPARG 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.