Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.61 |
| ▸ | PARP1 | P09874 | 4/20 | 0.61 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 6/20 | 0.60 |
| ▸ | TNKS | O95271 | 5/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695759 | 0.79 | TNKS2 (0.81) | TNKS2PARP1QTRT1GUSBTNKS | |
| SCHEMBL20898097 | 0.77 | MGLL (0.64) | — | |
| SCHEMBL3423481 | 0.77 | KDM4E (0.59) | TNKS2PARP1GUSBTNKSPARP2 | |
| SCHEMBL3037555 | 0.77 | TUBB4A (0.56) | TNKS2PARP1GUSBTNKSPARP2 | |
| SCHEMBL103994 | 0.76 | QTRT1 (1.00) | TNKS2PARP1QTRT1GUSBTNKS | |
| SCHEMBL22807316 | 0.76 | TNKS2 (0.61) | TNKS2PARP1QTRT1GUSBTNKS | |
| SCHEMBL894736 | 0.76 | TNKS2 (0.61) | TNKS2PARP1QTRT1GUSBTNKS | |
| SCHEMBL22021640 | 0.76 | TNKS2 (0.61) | TNKS2PARP1QTRT1GUSBTNKS | |
| Benzoylenurea SCHEMBL5110914 | 0.76 | TNKS2 (0.61) | TNKS2PARP1QTRT1GUSBTNKS | |
| SCHEMBL1772523 | 0.76 | TNKS2 (0.61) | TNKS2PARP1QTRT1GUSBTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660994-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-05-10 | — | — | CN | claimed |
| EP-3154962-A2 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | claimed |
| CN-106573922-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-04-19 | — | — | CN | claimed |
| CN-106459005-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105712940-A | Preparation method for Afatinib intermediate 6-nitryl-7-chlorol-4-quinazolinone | 南京师范大学 | 2016-06-29 | — | — | CN | claimed |
| WO-2015191754-A2 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | claimed |
| CN-1894234-A | Dipeptidyl peptidase inhibitors | SYRRX INC (JP) | 2007-01-10 | — | — | CN | claimed |
| EP-1608317-A4 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2006-12-27 | — | — | EP | claimed |
| EP-1608317-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda San Diego, Inc. (US) | 2005-12-28 | — | — | EP | claimed |
| US-20050004117-A1 | Dipeptidyl peptidase inhibitors | SYRRX, INC. | 2005-01-06 | — | — | US | claimed |
| WO-2004087053-A9 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX INC (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | claimed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | claimed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | claimed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| WO-2026098683-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | 盛睿泽华医药科技（苏州）有限公司 | 2026-05-15 | — | — | WO | disclosed |
| US-20260042754-A1 | Substituted Bicyclic Heteroaryl Sulfonamide Derivatives for the Treatment of Cancer | NODUS ONCOLOGY LIMITED (GB) | 2026-02-12 | — | — | US | disclosed |
| US-4141979-A | Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents | PFIZER INC. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4085213-A | Tetrazolo[A]quinazol-5-ones antiallergy and antiulcer agents | PFIZER INC. (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004117-A1 | Dipeptidyl peptidase inhibitors | DPP9, DPP4, DPP3 | TNKS2 4489/4885PARP1 3791/4885QTRT1 1768/4885 |
| US-20260042754-A1 | Substituted Bicyclic Heteroaryl Sulfonamide Derivatives for the Treatment of Cancer | CBR1, CBR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TNKS2 4054/4885PARP1 1418/4885QTRT1 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.