Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.63 |
| ▸ | MECP2 | P51608 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL16238468 | 0.98 | NOTUM (0.96) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL46426 | 0.83 | NPC1 (1.00) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2766462 | 0.82 | PKM (0.74) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL26673871 | 0.82 | NPC1 (0.78) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4343181 | 0.80 | NPC1 (0.94) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8650657 | 0.80 | RAB9A (1.00) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1143348 | 0.78 | KDM4E (1.00) | NOTUMNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15718167 | 0.78 | DGAT1 (1.00) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12550898 | 0.78 | KDM4E (0.66) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20767009 | 0.78 | NPC1 (0.72) | NOTUMNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031974-A | Ink for ink jet printing and electroluminescent device | 广东聚华印刷显示技术有限公司 | 2022-02-11 | — | — | CN | claimed |
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |
| CN-101437796-A | Piperidine derivatives, their process for preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101437795-A | Piperidine derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101437797-A | Piperidine derivatives, their process for preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| EP-4168399-B1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOMEDICAL CO LTD (CN) | 2026-04-01 | — | — | EP | disclosed |
| US-20250051293-A1 | NOVEL OXADIAZOLE DERIVATIVE AND USE THEREOF | CELROS BIOTECH (KR) | 2025-02-13 | — | — | US | disclosed |
| EP-4431498-A1 | NOVEL OXADIAZOLE DERIVATIVE AND USE THEREOF | Celros Biotech (KR) | 2024-09-18 | — | — | EP | disclosed |
| US-20240277683-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-08-22 | — | — | US | disclosed |
| CN-118525010-A | Novel oxadiazole derivative and use thereof | 赛罗斯生物科技 | 2024-08-20 | — | — | CN | disclosed |
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2007138033-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2007-12-06 | — | — | WO | disclosed |
| US-20070265265-A1 | N-(5-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2006022955-A2 | TOPOISOMERASE INHIBITORS | PROPHARMACON, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-6297385-B1 | EXHIBIT BOTH THE GOOD COUPLING KINETICS WHICH ARE REQUIRED FOR USE IN PHOTOGRAPHIC FILM MATERIALS, PARTICULARLY COLOR NEGATIVE FILM, AND ALSO AT THE SAME TIME EXHIBIT GOOD DARK FADING STABILITY, EXHIBIT A LOW HALF-BAND WIDTH. | AGFA-GEVAERT (BE) | 2001-10-02 | — | — | US | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277683-A1 | COMPOUNDS | SLC10A1, ABCB11, REN | NOTUM 398/4885NPC1 9/4885RAB9A 352/4885 |
| US-20250051293-A1 | NOVEL OXADIAZOLE DERIVATIVE AND USE THEREOF | NOX1, NOX3, NOX4 | NOTUM 4117/4885NPC1 2791/4885RAB9A 2971/4885 |
| US-20070265265-A1 | N-(5-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | ZC3HAV1, ZC3HAV1L, HAVCR2 | NOTUM 2474/4885NPC1 1259/4885RAB9A 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.