Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | XBP1 | P17861 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | AIP | O00170 | 1/20 | 0.62 |
| ▸ | SGTA | O43765 | 1/20 | 0.62 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.62 |
| ▸ | STIP1 | P31948 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453282 | 0.76 | AIP (0.71) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5451446 | 0.76 | AIP (0.71) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5460515 | 0.75 | AIP (0.69) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1066142 | 0.74 | FLT3 (0.68) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1067537 | 0.71 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8290603 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5454136 | 0.70 | REV1 (0.81) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL16445312 | 0.69 | CFTR (0.62) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL8293361 | 0.69 | PTPN1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5449182 | 0.68 | PDE4B (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | ALDH1A1 98/4885KDM4E 1784/4885HPGD 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.