TRAFD1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL21943538	0.59	1/20
SCHEMBL21943762	0.57	1/20
SCHEMBL21944043	0.55	1/20
SCHEMBL21943004	0.55	1/20
SCHEMBL21942995	0.53	1/20
SCHEMBL21943411	0.53	1/20
SCHEMBL21943429	0.52	1/20
SCHEMBL21943540	0.49	1/20
SCHEMBL21943537	0.45	1/20
SCHEMBL1454562	0.42	1/20
SCHEMBL17612956	0.42	1/20
SCHEMBL12399198	0.42	1/20
SCHEMBL29911712	0.40	1/20

Clinical trials — most relevant to TRAFD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19	PHASE2	UNKNOWN
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients	PHASE2	COMPLETED
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma	PHASE2	WITHDRAWN
Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children	PHASE1/PHASE2	COMPLETED
A Phase I Study Of Thymoglobulin In Patients With Relapsed Or Refractory Multiple Myeloma	PHASE1	COMPLETED
Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE	PHASE1	RECRUITING
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies	PHASE1	COMPLETED
Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC	EARLY_PHASE1	RECRUITING
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human	nan	UNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Immune Cell Response to Stimuli	nan	RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Tecfidera Diffusion Tensor Imaging	nan	COMPLETED
RNA Cloning and Visualization in Human Atherosclerosis	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus	nan	ACTIVE_NOT_RECRUITING
TL1A Expression in Psoriatic Skin	nan	UNKNOWN
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection	nan	UNKNOWN
Comparison of the Human Papillomavirus (HPV) Type 16 E7-Specific Immune Response Between a Normal Population and Patients With Cervical Lesions	nan	UNKNOWN
Pathogenetic Basis of Aortopathy and Aortic Valve Disease	nan	ACTIVE_NOT_RECRUITING
EKLF Gene Expression in β-thalassemia	nan	NOT_YET_RECRUITING
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients	nan	UNKNOWN
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins.	nan	UNKNOWN
Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies	nan	RECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TRAFD1 binder may also engage these)

Protein	Name	Similarity
Q4R970	—	1.000	Q4R970 →
Q99MM4	—	0.995	Q99MM4 →
Q58D05	—	0.992	Q58D05 →
Q3UDK1	—	0.990	Q3UDK1 →
Q6P2K3	—	0.978	Q6P2K3 →
Q8K2W6	—	0.975	Q8K2W6 →
Q501R9	—	0.974	Q501R9 →
Q6AYH3	—	0.972	Q6AYH3 →
Q9H706	—	0.972	Q9H706 →
Q62925	—	0.971	Q62925 →
Q5NVC7	—	0.971	Q5NVC7 →
Q14596	—	0.970	Q14596 →
Q8TEW8	—	0.969	Q8TEW8 →
Q5SUE8	—	0.969	Q5SUE8 →
Q5RC94	—	0.969	Q5RC94 →
P97432	—	0.969	P97432 →
Q9QXE4	—	0.968	Q9QXE4 →
Q8QFX1	—	0.968	Q8QFX1 →
Q5F3F2	—	0.968	Q5F3F2 →
B3KU38	—	0.968	B3KU38 →
Q8BIZ1	—	0.967	Q8BIZ1 →
P0DPB3	—	0.967	P0DPB3 →
P78314	—	0.967	P78314 →
Q3ZC82	—	0.967	Q3ZC82 →
Q8ND24	—	0.967	Q8ND24 →
Q7T321	—	0.967	Q7T321 →
Q06649	—	0.967	Q06649 →
Q53GL0	—	0.967	Q53GL0 →
Q6AI12	—	0.967	Q6AI12 →
Q99KR6	—	0.967	Q99KR6 →