Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSG101 | Q99816 | 16/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828661 | 0.95 | TSG101 (0.55) | TSG101PRMT5WDR77 | |
| SCHEMBL22958041 | 0.94 | TSG101 (0.53) | TSG101PRMT5WDR77 | |
| SCHEMBL19365089 | 0.91 | TSG101 (0.56) | TSG101PRMT5WDR77 | |
| SCHEMBL22958046 | 0.83 | TSG101 (0.46) | TSG101PRMT5WDR77 | |
| SCHEMBL12122167 | 0.83 | NAALAD2 (0.49) | PRMT5WDR77 | |
| SCHEMBL16904936 | 0.81 | TSG101 (0.46) | TSG101PRMT5WDR77 | |
| SCHEMBL7923683 | 0.79 | TSG101 (0.43) | TSG101PRMT5WDR77 | |
| SCHEMBL20647847 | 0.78 | NAALAD2 (0.50) | PRMT5WDR77 | |
| SCHEMBL21695192 | 0.77 | OPRD1 (0.47) | — | |
| SCHEMBL15828667 | 0.77 | ESR1 (0.51) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9358303-B2 | Compounds containing a vascular disrupting agent | INCANTHERA LTD (GB) | 2016-06-07 | — | — | US | disclosed |
| US-8927486-B2 | Compounds | INCANTHERA LIMITED (GB) | 2015-01-06 | — | — | US | disclosed |
| US-20140179592-A1 | Compounds | INCANTHERA LIMITED (GB) | 2014-06-26 | — | — | US | disclosed |
| US-20110275554-A1 | COMPOUNDS | THE UNIVERSITY OF BRADFORD (GB) | 2011-11-10 | — | — | US | disclosed |
| US-20100168036-A1 | GROWTH FACTOR | UNIVERSITY OF BRADFORD (GB) | 2010-07-01 | — | — | US | disclosed |
| US-20100168036-A1 | GROWTH FACTOR | UNIVERSITY OF BRADFORD (GB) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275554-A1 | COMPOUNDS | ADAM17, MMP3, MMP25 | TSG101 1043/4885PRMT5 2967/4885WDR77 4058/4885 |
| US-20100168036-A1 | GROWTH FACTOR | HDGF, VEGFA, PGF | TSG101 285/4885PRMT5 3996/4885WDR77 4623/4885 |
| US-20140179592-A1 | Compounds | MMP9, MMP3, MMP10 | TSG101 697/4885PRMT5 2207/4885WDR77 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.